Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 14/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 13/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18465038 | 0.81 | CA12 (0.41) | PTGS1PTGS2CA12CA1CA2 | |
| SCHEMBL22455897 | 0.78 | SLC22A12 (0.49) | PTGS1PTGS2NR3C1 | |
| SCHEMBL24435768 | 0.76 | PTGS1 (0.49) | PTGS1PTGS2CA12CA1CA2 | |
| SCHEMBL13468525 | 0.74 | ALDH1A1 (0.50) | NR3C1 | |
| SCHEMBL17737446 | 0.73 | LMNA (0.52) | — | |
| SCHEMBL21540857 | 0.72 | AOC1 (0.53) | PTGS1PTGS2 | |
| SCHEMBL18412744 | 0.72 | KMT2A (0.46) | — | |
| SCHEMBL14705314 | 0.70 | ALDH1A1 (0.54) | — | |
| SCHEMBL24435810 | 0.70 | NMT1 (0.46) | GRIA2NR3C1 | |
| SCHEMBL12649965 | 0.69 | CA1 (0.43) | NR3C1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020191205-A1 | PI4-KINASE INHIBITORS AND METHODS OF USING THE SAME | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-09-24 | — | — | WO | disclosed |