Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1420420 | 0.89 | DPP4 (0.32) | KDM4EMAPTTHRBDPP4GPR119 | |
| SCHEMBL1849221 | 0.77 | LIPE (0.32) | DPP4GPR119SCN9ASCN3ASCN5A | |
| SCHEMBL32684015 | 0.73 | GPR119 (0.36) | KDM4EMAPTTHRBGPR119NR1H2 | |
| SCHEMBL1847230 | 0.69 | PLAT (0.33) | KDM4EMAPTTHRBDPP4GPR119 | |
| SCHEMBL4236595 | 0.68 | GPR119 (0.32) | KDM4EMAPTTHRBGPR119SCN9A | |
| SCHEMBL2811594 | 0.68 | KDM4E (0.34) | KDM4EMAPTTHRBDPP4GPR119 | |
| SCHEMBL1420419 | 0.67 | GPR119 (0.33) | KDM4EMAPTTHRBDPP4GPR119 | |
| SCHEMBL6833620 | 0.64 | GPR119 (0.32) | KDM4EMAPTTHRBGPR119SCN9A | |
| SCHEMBL4236593 | 0.64 | PLAT (0.34) | KDM4EMAPTTHRBGPR119MEN1 | |
| SCHEMBL1849220 | 0.64 | PLAT (0.32) | KDM4EMAPTTHRBDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2324010-A1 | INSECTICIDAL PHENYL- OR PYRIDYL-PIPERIDINE COMPOUNDS | Syngenta Participations AG (CH) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010009968-A1 | INSECTICIDAL PHENYL- OR PYRIDYL-PIPERIDINE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-01-28 | — | — | WO | disclosed |