Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
| ▸ | KLK7 | P49862 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833619 | 0.74 | PLAT (0.34) | GPR119KDM4EMAPTTHRBPLAT | |
| SCHEMBL4236595 | 0.73 | GPR119 (0.32) | GPR119KDM4EMAPTTHRBNR1H2 | |
| SCHEMBL3073015 | 0.70 | GPR119 (0.33) | GPR119KDM4EMAPTTHRBNR1H2 | |
| SCHEMBL3729459 | 0.66 | GPR119 (0.36) | GPR119PLAT | |
| SCHEMBL16963473 | 0.66 | NR1H2 (0.59) | GPR119KDM4EMAPTTHRBNR1H2 | |
| SCHEMBL16963472 | 0.66 | NR1H2 (0.59) | GPR119KDM4EMAPTTHRBNR1H2 | |
| SCHEMBL1420420 | 0.66 | DPP4 (0.32) | GPR119KDM4EMAPTTHRBNR1H2 | |
| SCHEMBL4242556 | 0.65 | MEN1 (0.35) | GPR119KDM4EMAPTTHRBNR1H2 | |
| SCHEMBL10175516 | 0.65 | NR1H2 (0.58) | GPR119KDM4EMAPTTHRBNR1H2 | |
| Hydrochloric Acid SCHEMBL16052766 | 0.65 | NR1H2 (0.58) | GPR119KDM4EMAPTTHRBNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040044044-A1 | Thiazolyl urea compounds and methods of uses | AMGEN INC. | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044044-A1 | Thiazolyl urea compounds and methods of uses | SLC14A1, UMPS, BAX | GPR119 697/4885KDM4E 2714/4885MAPT 1437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.