Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GRN | P28799 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16841994 | 1.00 | KDM4E (0.43) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL16841996 | 0.84 | MAPT (0.57) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL13974014 | 0.84 | MAPT (0.57) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL17322650 | 0.83 | KDM4E (0.45) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL23730611 | 0.81 | SMN1; SMN2 (0.39) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL20353320 | 0.79 | GRN (0.35) | GRNSORT1 | |
| SCHEMBL14404899 | 0.78 | DPP4 (0.33) | GRNSORT1CTSLCTSSCTSB | |
| SCHEMBL20844329 | 0.75 | KDM4E (0.39) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL14111179 | 0.74 | NFKB1 (0.45) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL12661040 | 0.74 | NFKB1 (0.45) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170036980-A1 | COPPER CATALYZED [18F]FLUORINATION OF IODONIUM SALTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2017-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170036980-A1 | COPPER CATALYZED [18F]FLUORINATION OF IODONIUM SALTS | SOD1, TPO, FLI1 | KDM4E 4030/4885MAPT 2773/4885THRB 2221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.