Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | RORA | P35398 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | RORB | Q92753 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2453991 | 0.86 | PGR (0.55) | PGRRORARORCRORBKDM4E | |
| SCHEMBL1061987 | 0.85 | PGR (0.60) | PGRRORARORCRORBKDM4E | |
| SCHEMBL5263281 | 0.82 | PGR (0.50) | PGRRORARORCRORBKDM4E | |
| SCHEMBL17208787 | 0.81 | TOP2A (0.52) | TOP2AALDH1A1HIF1ANPSR1MAPT | |
| SCHEMBL18469659 | 0.78 | SLC6A4 (0.47) | SLC6A4SLC6A2HRH1 | |
| SCHEMBL11688278 | 0.76 | ALDH1A1 (0.51) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL6305077 | 0.76 | ALDH1A1 (0.59) | PGRRORARORCRORBKDM4E | |
| SCHEMBL11389425 | 0.74 | ALDH1A1 (0.51) | PGRRORARORCRORBTP53 | |
| SCHEMBL17208786 | 0.74 | ALDH1A1 (0.51) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL20968383 | 0.72 | ALDH1A1 (0.54) | ALDH1A1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170035893-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE | 2017-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170035893-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | AASDHPPT, CA13, CA12 | SLC6A4 2051/4885SLC6A2 1625/4885HRH1 1945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.