Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | RORA | P35398 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | RORB | Q92753 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1061987 | 0.90 | PGR (0.60) | PGRKDM4EGAARORARORC | |
| SCHEMBL2453991 | 0.89 | PGR (0.55) | PGRKDM4ERORARORCRORB | |
| SCHEMBL6305077 | 0.86 | ALDH1A1 (0.59) | PGRKDM4ERORARORCRORB | |
| SCHEMBL6232603 | 0.83 | ALDH1A1 (0.43) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL6233906 | 0.83 | ALDH1A1 (0.43) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL17208787 | 0.83 | TOP2A (0.52) | ALDH1A1NPSR1HPGDLMNAPOLB | |
| SCHEMBL5308775 | 0.83 | ALDH1A1 (0.55) | KDM4EALDH1A1NPSR1HPGDLMNA | |
| SCHEMBL6685738 | 0.82 | ALDH1A1 (0.41) | PGRKDM4ERORARORCRORB | |
| SCHEMBL6236721 | 0.82 | ALDH1A1 (0.67) | ALDH1A1NPSR1LMNATSHRMAPK1 | |
| SCHEMBL18474288 | 0.82 | SLC6A4 (0.49) | PGRKDM4ERORARORCRORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036604-A | Compound and application thereof | 中国药科大学 | 2026-05-15 | — | — | CN | disclosed |
| CN-110325540-A | Post-transcriptional chemically modified double-stranded RNA | 纳诺索尔公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-109943222-A | A kind of cross-linking type nano hybridization cyanic acid ester paint | 浙江中科应化科技有限公司 | 2019-06-28 | — | — | CN | disclosed |
| US-20070238763-A1 | Urea derivatives as integrin a4 antagonists | LABORATORIOS ALMIRALL, S.A. | 2007-10-11 | — | — | US | disclosed |
| EP-1383750-B1 | UREA DERIVATIVES AS INTEGRIN ALPHA 4 ANTAGONISTS | ALMIRALL LAB (ES) | 2007-09-26 | — | — | EP | disclosed |
| US-7253171-B2 | Urea derivatives as integrin α4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2007-08-07 | — | — | US | disclosed |
| US-20040142982-A1 | Urea derivatives as integrin alpha 4 antagonists | LABORATORIOS ALMIRALL, S.A. (ES) | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142982-A1 | Urea derivatives as integrin alpha 4 antagonists | ITGA4, ITGB4, ITGA1 | PGR 1895/4885KDM4E 1230/4885GAA 3296/4885 |
| US-20070238763-A1 | Urea derivatives as integrin a4 antagonists | ITGB4, ITGA4, ITGB7 | PGR 3910/4885KDM4E 615/4885GAA 3427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.