Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloromethane SCHEMBL11426935 | 0.81 | ACHE (0.44) | ACHECYP3A4TSHRLMNACA1 | |
| SCHEMBL13265364 | 0.81 | ACHE (0.44) | ACHECYP3A4TSHRLMNACA1 | |
| SCHEMBL1416559 | 0.80 | ACHE (0.48) | ACHECYP3A4TSHRLMNACA1 | |
| SCHEMBL9910588 | 0.78 | LMNA (0.48) | ACHECYP3A4TSHRLMNACA1 | |
| Methane SCHEMBL11149578 | 0.78 | ACHE (0.46) | ACHECYP3A4TSHRLMNACA1 | |
| SCHEMBL7556073 | 0.76 | LMNA (0.46) | ACHECYP3A4TSHRLMNACA1 | |
| SCHEMBL14371218 | 0.75 | LTA4H (0.41) | TSHRCA1CA2CA9TDP1 | |
| SCHEMBL13265269 | 0.75 | ACHE (0.48) | ACHECYP3A4TSHRLMNACA1 | |
| SCHEMBL2895268 | 0.74 | ACHE (0.48) | ACHECYP3A4TSHRLMNACA1 | |
| SCHEMBL969753 | 0.74 | ACHE (0.42) | ACHECYP3A4TSHRLMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331894-B1 | NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES AND THEIR USES | METRO INT BIOTECH LLC (US) | 2021-02-17 | — | — | EP | disclosed |
| WO-2017024255-A1 | NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES AND THEIR USES | METROBIOTECH, LLC (US) | 2017-02-09 | — | — | WO | disclosed |