Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 2/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.31 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26946628 | 0.88 | MME (0.34) | ERAP2SCN9AFOLH1SLC7A5BIRC2 | |
| SCHEMBL18476683 | 0.88 | MME (0.34) | ERAP2SCN9AFOLH1SLC7A5BIRC2 | |
| SCHEMBL25760733 | 0.88 | L3MBTL1 (0.42) | ERAP2SCN9A | |
| SCHEMBL20468541 | 0.84 | ANPEP (0.32) | ERAP2SCN9AFOLH1BIRC2MME | |
| SCHEMBL18451208 | 0.84 | CTSL (0.32) | ERAP2SCN9AFOLH1BIRC2ANPEP | |
| SCHEMBL20465427 | 0.84 | CTSL (0.32) | ERAP2SCN9AFOLH1BIRC2ANPEP | |
| SCHEMBL18478760 | 0.84 | L3MBTL1 (0.39) | ERAP2BIRC2 | |
| SCHEMBL25760735 | 0.84 | FOLH1 (0.46) | ERAP2FOLH1SLC7A5MME | |
| SCHEMBL21473358 | 0.82 | BIRC2 (0.33) | ERAP2FOLH1BIRC2 | |
| SCHEMBL20465433 | 0.82 | CTSB (0.37) | ERAP2BIRC2ANPEPRNPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328827-B1 | PRODRUGS OF GLUTAMINE ANALOGS | UNIV JOHNS HOPKINS (US) | 2023-07-05 | — | — | EP | disclosed |
| WO-2017023774-A9 | PRODRUGS OF GLUTAMINE ANALOGS | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-11-23 | — | — | WO | disclosed |
| WO-2017023774-A1 | PRODRUGS OF GLUTAMINE ANALOGS | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-02-09 | — | — | WO | disclosed |