Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.38 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 5/20 | 0.33 |
| ▸ | METAP1 | P53582 | 3/20 | 0.33 |
| ▸ | CAD | P27708 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18478760 | 0.96 | L3MBTL1 (0.39) | L3MBTL1KMT2APOLBNOD1PPID | |
| SCHEMBL18478758 | 0.88 | ERAP2 (0.33) | ERAP2SCN9A | |
| SCHEMBL25760765 | 0.88 | L3MBTL1 (0.42) | L3MBTL1KMT2APOLBNOD1PPID | |
| SCHEMBL18478761 | 0.87 | L3MBTL1 (0.46) | L3MBTL1KMT2APOLBNOD1METAP2 | |
| SCHEMBL29465612 | 0.84 | L3MBTL1 (0.39) | L3MBTL1KMT2APOLBNOD1PPID | |
| SCHEMBL21473367 | 0.84 | L3MBTL1 (0.39) | L3MBTL1KMT2APOLBNOD1PPID | |
| SCHEMBL18452348 | 0.84 | L3MBTL1 (0.39) | L3MBTL1KMT2APOLBNOD1PPID | |
| SCHEMBL20468520 | 0.84 | L3MBTL1 (0.39) | L3MBTL1KMT2APOLBNOD1PPID | |
| SCHEMBL20465429 | 0.84 | L3MBTL1 (0.39) | L3MBTL1KMT2APOLBNOD1PPID | |
| SCHEMBL25760735 | 0.84 | FOLH1 (0.46) | KMT2ANOD1ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328827-B1 | PRODRUGS OF GLUTAMINE ANALOGS | UNIV JOHNS HOPKINS (US) | 2023-07-05 | — | — | EP | disclosed |