Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CAD | P27708 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 6/20 | 0.36 |
| ▸ | METAP1 | P53582 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25760733 | 0.87 | L3MBTL1 (0.42) | L3MBTL1KMT2APOLBNOD1CAD | |
| SCHEMBL20468545 | 0.86 | L3MBTL1 (0.46) | L3MBTL1KMT2APOLBNOD1DPP8 | |
| SCHEMBL18478760 | 0.84 | L3MBTL1 (0.39) | L3MBTL1KMT2APOLBNOD1SMN1; SMN2 | |
| SCHEMBL20465422 | 0.83 | L3MBTL1 (0.43) | L3MBTL1KMT2APOLBNOD1DPP8 | |
| SCHEMBL20468542 | 0.83 | L3MBTL1 (0.43) | L3MBTL1KMT2APOLBNOD1DPP8 | |
| SCHEMBL18451341 | 0.83 | L3MBTL1 (0.43) | L3MBTL1KMT2APOLBNOD1DPP8 | |
| SCHEMBL18478762 | 0.82 | NOD1 (0.51) | NOD1DPP8DPP7 | |
| SCHEMBL19114277 | 0.77 | SMN1; SMN2 (0.57) | L3MBTL1KMT2APOLBSMN1; SMN2KDM4E | |
| SCHEMBL18476661 | 0.76 | TSHR (0.39) | L3MBTL1KMT2APOLBNOD1ALDH1A1 | |
| SCHEMBL4560808 | 0.76 | CAD (0.44) | L3MBTL1KMT2APOLBDPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328827-B1 | PRODRUGS OF GLUTAMINE ANALOGS | UNIV JOHNS HOPKINS (US) | 2023-07-05 | — | — | EP | disclosed |
| WO-2017023774-A9 | PRODRUGS OF GLUTAMINE ANALOGS | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-11-23 | — | — | WO | disclosed |
| WO-2017023774-A1 | PRODRUGS OF GLUTAMINE ANALOGS | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-02-09 | — | — | WO | disclosed |