Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20465780 | 1.00 | LRRK2 (0.36) | LRRK2EPHX1EPHX2KDM1ANR3C2 | |
| SCHEMBL18438174 | 0.82 | ALDH1A1 (0.36) | EPHX2ALDH1A1L3MBTL1 | |
| SCHEMBL18479684 | 0.80 | GPR119 (0.46) | EPHX1ALDH1A1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL23849639 | 0.77 | ITGB3 (0.34) | DPP8DPP7 | |
| Trifluoroacetic Acid SCHEMBL23849603 | 0.77 | ITGB3 (0.34) | DPP8DPP7 | |
| SCHEMBL18477424 | 0.76 | ACHE (0.34) | — | |
| SCHEMBL23863906 | 0.76 | ACHE (0.34) | — | |
| SCHEMBL20465792 | 0.75 | TDP1 (0.31) | — | |
| SCHEMBL20465789 | 0.75 | TDP1 (0.31) | — | |
| SCHEMBL20465787 | 0.75 | TDP1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017021729-A1 | MUSCARINIC AGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2017-02-09 | — | — | WO | disclosed |