Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12220455 | 0.87 | KMT2A (0.46) | ALDH1A1KMT2AGAAMAPTMEN1 | |
| SCHEMBL29489700 | 0.80 | LMNA (0.42) | ALDH1A1KMT2AGAAMAPTMEN1 | |
| SCHEMBL12220454 | 0.78 | KMT2A (0.43) | ALDH1A1KMT2AGAAMAPTMEN1 | |
| SCHEMBL21387159 | 0.70 | MGLL (0.41) | ALDH1A1KMT2AGAAMAPTMEN1 | |
| SCHEMBL2714721 | 0.70 | MGLL (0.41) | ALDH1A1KMT2AGAAMEN1GSK3A | |
| SCHEMBL18481365 | 0.70 | ITGA4 (0.51) | ALDH1A1KMT2AGAAMAPTMEN1 | |
| SCHEMBL419811 | 0.70 | KMT2A (1.00) | ALDH1A1KMT2AGAAMAPTMEN1 | |
| SCHEMBL13716111 | 0.70 | NR1H4 (0.44) | ALDH1A1KMT2AGAAMEN1LMNA | |
| SCHEMBL9655840 | 0.70 | GSK3A (0.39) | ALDH1A1KMT2AGAAMEN1LMNA | |
| SCHEMBL13966825 | 0.70 | NR1H4 (0.44) | ALDH1A1KMT2AGAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240277714-A1 | USE OF SOS1 INHIBITORS WITH RAS INHIBITORS TO TREAT CANCERS | Revolution Medicines, Inc. | 2024-08-22 | — | — | US | disclosed |
| US-20240108630-A1 | METHODS FOR INHIBITING RAS | Revolution Medicines, Inc. | 2024-04-04 | — | — | US | disclosed |
| US-20220235134-A1 | ANTI-B7-H3 ANTIBODIES | SINGLE CELL TECHNOLOGY, INC. (US) | 2022-07-28 | — | — | US | disclosed |
| EP-3976660-A1 | ANTI-B7-H3 ANTIBODIES | Single Cell Technology, Inc. (US) | 2022-04-06 | — | — | EP | disclosed |
| US-8039532-B2 | Heterocyclic compound, ultraviolet absorbent and composition containing the same | FUJIFILM CORPORATION (JP) | 2011-10-18 | — | — | US | disclosed |
| US-20100210762-A1 | HETEROCYCLIC COMPOUND, ULTRAVIOLET ABSORBENT AND COMPOSITION CONTAINING THE SAME | FUJIFILM CORPORATION (JP) | 2010-08-19 | — | — | US | disclosed |
| US-20090240067-A1 | METHOD OF PRODUCING A BISBENZODITHIOL COMPOUND | FUJIFILM CORPORATION (JP) | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210762-A1 | HETEROCYCLIC COMPOUND, ULTRAVIOLET ABSORBENT AND COMPOSITION CONTAINING THE SAME | F12, F2, CYP24A1 | ALDH1A1 1492/4885KMT2A 4498/4885GAA 4733/4885 |
| US-20090240067-A1 | METHOD OF PRODUCING A BISBENZODITHIOL COMPOUND | SQOR, NQO1, PBRM1 | ALDH1A1 739/4885KMT2A 1603/4885GAA 3775/4885 |
| US-20240277714-A1 | USE OF SOS1 INHIBITORS WITH RAS INHIBITORS TO TREAT CANCERS | SOS1, HRAS, KRAS | ALDH1A1 4139/4885KMT2A 3126/4885GAA 2621/4885 |
| US-20240108630-A1 | METHODS FOR INHIBITING RAS | KRAS, HRAS, NRAS | ALDH1A1 4098/4885KMT2A 2355/4885GAA 2220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.