Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17830829 | 0.81 | SLC6A2 (0.50) | CHRNA7ALDH1A1TSHRALOX5KDM4E | |
| SCHEMBL16373314 | 0.81 | SLC2A1 (0.50) | UTS2RALDH1A1TSHRALOX5L3MBTL1 | |
| SCHEMBL19618141 | 0.74 | CHRNA7 (0.48) | S1PR1CHRNA7ALDH1A1TSHRALOX5 | |
| SCHEMBL5301480 | 0.73 | ALDH1A1 (0.47) | ADRB2ALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL9874672 | 0.73 | ADRB2 (0.52) | ADRB2TSHRKDM4ELMNASLC6A2 | |
| SCHEMBL15423680 | 0.73 | ADRB2 (0.52) | ADRB2CHRNA7TSHRLMNACES2 | |
| SCHEMBL14435622 | 0.73 | ADRB2 (0.52) | ADRB2TSHRKDM4ELMNASLC6A2 | |
| SCHEMBL20169678 | 0.72 | ADRB2 (0.46) | ADRB2UTS2RTSHRCES2CES1 | |
| SCHEMBL20386671 | 0.71 | CHRNA7 (0.44) | CHRNA7ALDH1A1TSHRALOX5KDM4E | |
| SCHEMBL12367721 | 0.71 | CHRNA7 (0.44) | CHRNA7ALDH1A1TSHRALOX5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9650310-B2 | Method for the methylation of nitrogen-containing organic compounds | RHEINISCHE-WESTFÄLISCHE TECHNISCHE HOCHSCHULE (RWTH) AACHEN (DE) | 2017-05-16 | — | — | US | disclosed |
| US-20160168043-A1 | METHOD FOR THE METHYLATION OF NITROGEN-CONTAINING ORGANIC COMPOUNDS | RHEINISCHE-WESTFÄLISCHE TECHNISCHE HOCHSCHULE (RWTH) AACHEN (DE) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168043-A1 | METHOD FOR THE METHYLATION OF NITROGEN-CONTAINING ORGANIC COMPOUNDS | HNMT, PNMT, GNMT | S1PR1 4340/4885ADRB2 1734/4885CHRNA7 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.