Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14805638 | 0.84 | SRC (0.42) | SRCARKDM4EUSP2ALDH1A1 | |
| SCHEMBL1119200 | 0.80 | GPR35 (0.45) | ARKDM4EUSP2ALDH1A1POLB | |
| SCHEMBL2677978 | 0.80 | CYP1A2 (0.44) | CYP1A2CYP1A1CYP1B1ALDH1A1ACHE | |
| SCHEMBL31432852 | 0.80 | ACHE (0.61) | SRCARKDM4EUSP2ALDH1A1 | |
| SCHEMBL4406542 | 0.80 | AR (0.45) | SRCARKDM4EUSP2ALDH1A1 | |
| SCHEMBL4694671 | 0.80 | AR (0.49) | SRCARKDM4EUSP2ALDH1A1 | |
| SCHEMBL18245208 | 0.80 | CYP1A2 (0.44) | CYP1A2CYP1A1CYP1B1ALDH1A1ACHE | |
| SCHEMBL20589615 | 0.78 | KDM4E (0.59) | SRCKDM4EUSP2ALDH1A1HPGD | |
| SCHEMBL31095269 | 0.78 | KDM4E (0.59) | SRCKDM4EUSP2ALDH1A1HPGD | |
| SCHEMBL2390290 | 0.78 | ALOX15 (0.43) | SRCARKDM4EUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170037059-A1 | GYRASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2017-02-09 | — | — | US | disclosed |
| CN-1604778-A | Cis-imidazolines as MDM2 inhibitors | HOFFMANN LA ROCHE (CH) | 2005-04-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037059-A1 | GYRASE INHIBITORS | TOP1, CA7, TOP2B | SRC 1873/4885AR 2395/4885CYP1A2 571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.