Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31386976 | 0.82 | ALDH1A1 (0.43) | ALDH1A1TSHR | |
| SCHEMBL31537920 | 0.77 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL4921825 | 0.74 | HPGD (0.34) | — | |
| SCHEMBL31053791 | 0.74 | TSHR (0.47) | ALDH1A1TSHRTHRB | |
| Butane SCHEMBL1155320 | 0.73 | TSHR (0.43) | ALDH1A1TSHR | |
| SCHEMBL8903601 | 0.71 | ALDH1A1 (0.41) | ALDH1A1TSHRTHRB | |
| SCHEMBL16401460 | 0.70 | MEN1 (0.30) | — | |
| SCHEMBL7629107 | 0.70 | ALDH1A1 (0.40) | ALDH1A1TSHRTHRB | |
| SCHEMBL7819809 | 0.69 | MMP1 (0.36) | ALDH1A1 | |
| SCHEMBL9681593 | 0.69 | ALDH1A1 (0.33) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2324028-A2 | THERAPEUTIC AGENTS 414 | AstraZeneca AB (SE) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010015849-A2 | THERAPEUTIC AGENTS 414 | ASTRAZENECA AB (SE) | 2010-02-11 | — | — | WO | disclosed |