Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.35 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18483481 | 0.83 | IDO1 (0.35) | PDE10A | |
| SCHEMBL18448789 | 0.73 | CYP4F2 (0.49) | PDE10A | |
| SCHEMBL18448289 | 0.71 | NPC1 (0.55) | PDE10A | |
| SCHEMBL18447768 | 0.70 | LMNA (0.36) | PDE10A | |
| SCHEMBL18448780 | 0.67 | PDE10A (0.35) | PDE10A | |
| SCHEMBL22271059 | 0.63 | KDM4A (0.37) | SQOR | |
| SCHEMBL18447639 | 0.63 | MAOB (0.53) | — | |
| SCHEMBL18448243 | 0.63 | EP300 (0.44) | — | |
| SCHEMBL10726634 | 0.62 | ALDH1A1 (0.53) | PDE10A | |
| SCHEMBL18448284 | 0.62 | LMNA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017021879-A1 | NOVEL COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2017-02-09 | — | — | WO | disclosed |