Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15570883 | 0.92 | LMNA (0.44) | LMNASLC15A2MEN1KMT2AHIF1A | |
| SCHEMBL3574845 | 0.82 | ALDH1A1 (0.42) | LMNAMEN1KMT2AHIF1ABLM | |
| SCHEMBL9348946 | 0.81 | MEN1 (0.39) | LMNAMEN1KMT2AHIF1ABLM | |
| SCHEMBL17281804 | 0.80 | TSHR (0.40) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11373249 | 0.79 | PPARG (0.47) | MEN1KMT2AALDH1A1ESR1TSHR | |
| SCHEMBL15443091 | 0.75 | LMNA (0.44) | LMNAMEN1KMT2AHIF1ABLM | |
| SCHEMBL9334375 | 0.75 | ALDH1A1 (0.47) | LMNASLC15A2MEN1KMT2AHIF1A | |
| SCHEMBL44822 | 0.75 | ALDH1A1 (0.47) | LMNASLC15A2MEN1KMT2AHIF1A | |
| SCHEMBL3998009 | 0.74 | LMNA (0.48) | LMNASLC15A2MEN1KMT2AHIF1A | |
| SCHEMBL4162551 | 0.74 | LMNA (0.48) | LMNASLC15A2MEN1KMT2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708242-B2 | Method of manufacturing nitrone compound | NATIONAL CHUNG CHENG UNIVERSITY (TW) | 2017-07-18 | — | — | US | disclosed |
| US-20170036989-A1 | Method of Manufacturing Nitrone Compound | NATIONAL CHUNG CHENG UNIVERSITY | 2017-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170036989-A1 | Method of Manufacturing Nitrone Compound | NOS1, NOS2, NOX5 | LMNA 804/4885SLC15A2 4551/4885MEN1 2003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.