Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.56 |
| ▸ | ADK | P55263 | 2/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.47 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18483493 | 1.00 | DOT1L (0.56) | DOT1LADKPAX8HIF1ADNMT1 | |
| SCHEMBL18484348 | 0.88 | HIF1A (0.54) | DOT1LADKPAX8HIF1ADNMT1 | |
| SCHEMBL22159896 | 0.88 | HIF1A (0.54) | DOT1LADKPAX8HIF1ADNMT1 | |
| SCHEMBL18483516 | 0.88 | DOT1L (0.54) | DOT1LADKPAX8HIF1ADNMT1 | |
| SCHEMBL11526151 | 0.87 | ADK (0.56) | DOT1LADKPAX8HIF1ADNMT1 | |
| SCHEMBL18483520 | 0.87 | HIF1A (0.53) | DOT1LADKPAX8HIF1AALDH1A1 | |
| SCHEMBL18484339 | 0.85 | HIF1A (0.52) | DOT1LADKPAX8HIF1ADNMT1 | |
| SCHEMBL18483514 | 0.84 | ADK (0.58) | DOT1LADKPAX8HIF1ADNMT1 | |
| SCHEMBL18874621 | 0.83 | ADK (0.50) | DOT1LADKPAX8HIF1ADNMT1 | |
| Water SCHEMBL20840353 | 0.83 | ALDH1A1 (0.56) | DOT1LADKPAX8HIF1ADNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017024310-A1 | PYRROLOPYRIMIDINE NUCLEOSIDES AND ANALOGS THEREOF USEFUL AS ANTIVIRAL AGENTS | CHIMERIX, INC. (US) | 2017-02-09 | — | — | WO | disclosed |