Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.52 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.52 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | HTR3B | O95264 | 1/20 | 0.52 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.52 |
| ▸ | CHRNG | P07510 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1848736 | 1.00 | ALDH1A1 (0.52) | ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL29398395 | 1.00 | ALDH1A1 (0.52) | ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL524734 | 0.80 | ALDH1A1 (0.56) | ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL523445 | 0.80 | ALDH1A1 (0.56) | ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL29766108 | 0.80 | ALDH1A1 (0.64) | ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL30618802 | 0.80 | ALDH1A1 (0.64) | ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9366878 | 0.79 | PTGS1 (0.52) | PTGS1 | |
| SCHEMBL29173751 | 0.78 | CHRNA7 (0.62) | ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5249340 | 0.78 | CHRNA7 (0.62) | ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL30866542 | 0.78 | CHRNA7 (0.62) | ALDH1A1CHRNA7CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718929-B2 | Chelating amphiphilic polymers | KONINKLIJKE PHILIPS N.V. (NL) | 2017-08-01 | — | — | US | disclosed |
| CN-102149371-B | Chelating amphiphilic polymers | 皇家飞利浦电子股份有限公司 | 2017-04-19 | — | — | CN | disclosed |
| US-20150247008-A1 | CHELATING AMPHIPHILIC POLYMERS | KONINKL PHILIPS NV (NL) | 2015-09-03 | — | — | US | disclosed |
| EP-2323636-B1 | CHELATING AMPHIPHILIC POLYMERS | KONINKL PHILIPS NV (NL) | 2015-08-12 | — | — | EP | disclosed |
| US-9034298-B2 | Chelating amphiphilic polymers | KONINKLIJKE PHILIPS N.V. (NL) | 2015-05-19 | — | — | US | disclosed |
| CN-102149371-A | Chelating amphiphilic polymers | KONINKL PHILIPS ELECTRONICS NV | 2011-08-10 | — | — | CN | disclosed |
| US-20110165074-A1 | CHELATING AMPHIPHILIC POLYMERS | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2011-07-07 | — | — | US | disclosed |
| EP-2323636-A1 | CHELATING AMPHIPHILIC POLYMERS | Koninklijke Philips Electronics N.V. (NL) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010029500-A1 | CHELATING AMPHIPHILIC POLYMERS | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2010-03-18 | — | — | WO | disclosed |
| EP-2161020-A1 | Chelating amphiphilic polymers | Koninklijke Philips Electronics N.V. (NL) | 2010-03-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150247008-A1 | CHELATING AMPHIPHILIC POLYMERS | SLC30A5, SLC30A6, ABCB4 | ALDH1A1 4768/4885CHRNA7 3618/4885CHRNB2 2880/4885 |
| US-20110165074-A1 | CHELATING AMPHIPHILIC POLYMERS | SLC30A5, PICALM, SLC30A6 | ALDH1A1 4789/4885CHRNA7 3586/4885CHRNB2 3082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.