Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | CCR4 | P51679 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | STK17B | O94768 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18488676 | 0.84 | TAAR1 (0.46) | GPR84KMT2ASTK17ASTK17BTAAR1 | |
| SCHEMBL18488333 | 0.84 | GPR84 (0.46) | GPR84KMT2AIGF1RSTK17AALDH1A1 | |
| SCHEMBL20668014 | 0.78 | GPR84 (0.37) | GPR84KMT2AALDH1A1AKT3PTGDR | |
| SCHEMBL18488361 | 0.77 | CYP2D6 (0.49) | STK17ASTK17BTAAR1 | |
| SCHEMBL18488975 | 0.74 | PGK1 (0.48) | ALDH1A1TAAR1 | |
| SCHEMBL18492638 | 0.70 | ALK (0.61) | IGF1R | |
| SCHEMBL9921326 | 0.68 | HTT (0.44) | GPR84KMT2AALDH1A1HPGD | |
| SCHEMBL19700804 | 0.68 | TP53 (0.61) | KMT2AALDH1A1HPGD | |
| SCHEMBL680436 | 0.67 | TAAR1 (0.60) | GPR84KMT2AALDH1A1CNR1TAAR1 | |
| SCHEMBL18488672 | 0.67 | MEN1 (0.50) | GPR84KMT2ASTK17ASTK17BTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017023899-A1 | INHIBITORS OF ACK1/TNK2 TYROSINE KINASE | H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE (US) | 2017-02-09 | — | — | WO | disclosed |