Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL1844305 | 0.96 | CA1 (0.44) | CA1CA2CA9MAPTGPR84 | |
| Lithium Ion SCHEMBL1846541 | 0.96 | CA1 (0.44) | CA1CA2CA9MAPTGPR84 | |
| Zinc Ion SCHEMBL4623990 | 0.96 | CA1 (0.44) | CA1CA2CA9MAPTGPR84 | |
| SCHEMBL402058 | 0.96 | GPR84 (0.47) | CA1CA2CA9MAPTGPR84 | |
| SCHEMBL8659995 | 0.96 | GPR84 (0.47) | CA1CA2CA9MAPTGPR84 | |
| SCHEMBL1843881 | 0.96 | LMNA (0.46) | CA1CA2CA9MAPTGPR84 | |
| SCHEMBL1846850 | 0.96 | CA1 (0.44) | CA1CA2CA9MAPTGPR84 | |
| SCHEMBL4622060 | 0.88 | CA1 (0.44) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL5076709 | 0.86 | CA1 (0.46) | CA1CA2CA9MAPTALDH1A1 | |
| Zinc Ion SCHEMBL4622731 | 0.84 | CA1 (0.44) | CA1CA2CA9MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337566-B1 | FILMS, COMPOSITIONS AND PROCESSES | UCB SA (BE) | 2005-12-14 | — | — | EP | claimed |
| US-6969556-B2 | Films, compositions and processes | UCB, S.A. (BE) | 2005-11-29 | — | — | US | claimed |
| EP-2883925-B1 | Polypropylene based composition | REPSOL SA (ES) | 2016-10-05 | — | — | EP | disclosed |
| EP-2267045-B1 | Olefin polymer of very low polydispersity and process for preparing the same | MITSUI CHEMICALS INC (JP) | 2015-07-15 | — | — | EP | disclosed |
| EP-2267041-B1 | Olefin multiblock copolymer of very low polydispersity and process for preparing the same | MITSUI CHEMICALS INC (JP) | 2015-07-08 | — | — | EP | disclosed |
| EP-2267044-B1 | Olefin polymer of very low polydispersity and process for preparing the same | MITSUI CHEMICALS INC (JP) | 2015-07-08 | — | — | EP | disclosed |
| EP-2883925-A1 | Polypropylene based composition | Repsol, S.A. (ES) | 2015-06-17 | — | — | EP | disclosed |
| US-8436089-B2 | Polypropylene composition, a method of producing the same, and articles made therefrom | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-05-07 | — | — | US | disclosed |
| US-8338557-B2 | Olefin polymer and process for preparing the same | MITSUI CHEMICALS, INC. (JP) | 2012-12-25 | — | — | US | disclosed |
| EP-2142596-B1 | A POLYPROPYLENE COMPOSITION, A METHOD OF PRODUCING THE SAME, AND ARTICLES MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-10-26 | — | — | EP | disclosed |
| EP-1162211-B2 | ETHYLENE (CO)POLYMERS AND USES THEREOF | MITSUI CHEMICALS INC (JP) | 2011-08-24 | — | — | EP | disclosed |
| US-5595827-A | BLEND WITH POLYTERPENE AND/OR PETROLEUM RESIN, MULTILAYER FILM FOR PACKAGING, WATER VAPOR BARRIER | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-21 | — | — | US | disclosed |
| EP-0634455-B1 | Polypropylene resin composition and the use of the same | MITSUI PETROCHEMICAL IND (JP) | 1997-01-08 | — | — | EP | disclosed |
| EP-0361087-B1 | Crystalline polyolefin composition | CHISSO CORP (JP) | 1996-07-10 | — | — | EP | disclosed |
| EP-0716121-A1 | Composition of polypropylene with propylene-butene elastomer | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-06-12 | — | — | EP | disclosed |
| US-5412020-A | Impact strength | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0636650-A1 | Propylene polymer compositions | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-01 | — | — | EP | disclosed |
| EP-0634455-A1 | Polypropylene resin composition and the use of the same | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-01-18 | — | — | EP | disclosed |
| US-5001176-A | Crystalline polyolefin composition | CHISSO CORPORATION (JP) | 1991-03-19 | — | — | US | disclosed |
| EP-0361087-A2 | Crystalline polyolefin composition | CHISSO CORPORATION (JP) | 1990-04-04 | — | — | EP | disclosed |