Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.44 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659995 | 1.00 | GPR84 (0.47) | GPR84CA1CA2CA9MAPT | |
| Lithium Ion SCHEMBL1846541 | 0.96 | CA1 (0.44) | GPR84CA1CA2CA9MAPT | |
| Zinc Ion SCHEMBL4623990 | 0.96 | CA1 (0.44) | GPR84CA1CA2CA9MAPT | |
| Potassium Ion SCHEMBL1844305 | 0.96 | CA1 (0.44) | GPR84CA1CA2CA9MAPT | |
| SCHEMBL1846850 | 0.96 | CA1 (0.44) | GPR84CA1CA2CA9MAPT | |
| SCHEMBL1843881 | 0.96 | LMNA (0.46) | GPR84CA1CA2CA9MAPT | |
| SCHEMBL1849356 | 0.96 | CA1 (0.44) | GPR84CA1CA2CA9MAPT | |
| SCHEMBL5076709 | 0.90 | CA1 (0.46) | CA1CA2CA9MAPTALDH1A1 | |
| Zinc Ion SCHEMBL4622731 | 0.88 | CA1 (0.44) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL4624139 | 0.88 | LMNA (0.46) | CA1CA2CA9MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260146151-A1 | ALPHA-NUCLEATED PROPYLENE/ETHYLENE/1-BUTENE TERPOLYMER COMPOSITIONS FOR BLOWN AND CAST FILMS | BOREALIS AG (AT) | 2026-05-28 | — | — | US | claimed |
| CN-121574530-A | PC composite material with low warpage and preparation method and application thereof | 重庆会通科技有限公司 | 2026-02-27 | — | — | CN | claimed |
| CN-119744282-A | Alpha-nucleated propylene/ethylene/1-butene terpolymer compositions for blown and cast films | 博里利斯股份公司 | 2025-04-01 | — | — | CN | claimed |
| CN-118852830-A | Polypropylene composite additive capable of improving polypropylene glossiness and preparation method thereof | 涿州市隽诚化工有限公司 | 2024-10-29 | — | — | CN | claimed |
| CN-118056866-A | Polyolefin film material, polyolefin film and polyolefin aluminized film | 中国石油化工股份有限公司 | 2024-05-21 | — | — | CN | claimed |
| CN-116144100-B | Low-temperature-resistant thin-wall high-length-diameter-ratio polypropylene ribbon | 张家港绿洲新材料科技有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-115678161-B | Composite nucleating agent composition and application thereof | 呈和科技股份有限公司 | 2024-04-12 | — | — | CN | claimed |
| WO-2024042070-A1 | ALPHA-NUCLEATED PROPYLENE/ETHYLENE/1-BUTENE TERPOLYMER COMPOSITIONS FOR BLOWN AND CAST FILMS | BOREALIS AG (AT) | 2024-02-29 | — | — | WO | claimed |
| CN-114427124-B | Antibacterial flame-retardant polypropylene fiber composition, preparation method thereof, fiber and non-woven fabric | 中国石油化工股份有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-114716784-B | Masterbatch for preparing polypropylene ribbon and preparation method and application thereof | 张家港绿洲新材料科技有限公司 | 2024-01-09 | — | — | CN | claimed |
| US-4891397-A | POLYBUTYLENE TEREPHTHALATE | GENERAL ELECTRIC COMPANY (US) | 1990-01-02 | — | — | US | claimed |
| EP-0318788-A2 | Improved nucleated thermoplastic copolyetherester molding compositions | GENERAL ELECTRIC COMPANY (US) | 1989-06-07 | — | — | EP | claimed |
| EP-0318786-A1 | Improved nucleated thermoplastic polyetherimide ester elastomer molding compositions | GENERAL ELECTRIC COMPANY (US) | 1989-06-07 | — | — | EP | claimed |
| EP-0312976-A2 | Styrene-based resin composition and process for production of moldings | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1989-04-26 | — | — | EP | claimed |
| US-4808396-A | GEL CONTAINING A TERPENE | RICOH COMPANY, LTD. (JP) | 1989-02-28 | — | — | US | claimed |
| EP-0278409-A2 | Glass fiber reinforced polyolefin resin composition | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1988-08-17 | — | — | EP | claimed |
| EP-0265075-A2 | Polypropylene resin composition | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-04-27 | — | — | EP | claimed |
| US-4708800-A | POLYPROPYLENE; ARTIFICIAL LUNG | TERUMO KABUSHIKI KAISHA (JP) | 1987-11-24 | — | — | US | claimed |
| US-4650816-A | AGENT FOR INCREASING RATE OF CRYSTALLIZATION | MONTEFINA, S.A. (BE) | 1987-03-17 | — | — | US | claimed |
| US-4585817-A | LINEAR LOW DENSITY ETHYLENE POLYMERS | MOBIL OIL CORPORATION (US) | 1986-04-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260146151-A1 | ALPHA-NUCLEATED PROPYLENE/ETHYLENE/1-BUTENE TERPOLYMER COMPOSITIONS FOR BLOWN AND CAST FILMS | LBR, NCLN, NUP50 | CA1 2347/4885CA2 3242/4885GPR84 4818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.