Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.46 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622060 | 0.98 | CA1 (0.44) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL28934781 | 0.98 | CA1 (0.44) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL4624139 | 0.98 | LMNA (0.46) | CA1CA2CA9MAPTALDH1A1 | |
| Zinc Ion SCHEMBL4622731 | 0.98 | CA1 (0.44) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL8659995 | 0.90 | GPR84 (0.47) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL402058 | 0.90 | GPR84 (0.47) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL30461570 | 0.86 | MAPT (0.45) | CA1CA2CA9MAPTALDH1A1 | |
| Potassium Ion SCHEMBL1844305 | 0.86 | CA1 (0.44) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL1846850 | 0.86 | CA1 (0.44) | CA1CA2CA9MAPTALDH1A1 | |
| Zinc Ion SCHEMBL4623990 | 0.86 | CA1 (0.44) | CA1CA2CA9MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549246-A | Hyperbranched microcrystalline nucleating agent composition and application thereof | 中化石化销售有限公司 | 2021-10-26 | — | — | CN | claimed |
| CN-113444343-A | Preparation method of hyperbranched microcrystalline nucleating agent and preparation method of polyolefin resin | 中化石化销售有限公司 | 2021-09-28 | — | — | CN | claimed |
| CN-113549246-B | Hyperbranched microcrystalline nucleating agent composition and application | 中化石化销售有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-113444343-B | Preparation method of hyperbranched microcrystalline nucleating agent and preparation method of polyolefin resin | 中化石化销售有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-110337356-B | Adhesive article comprising polylactic acid polymer film and method of making the same | 3M创新有限公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-109312096-B | Foam compositions comprising polylactic acid polymers, polyvinyl acetate polymers, and plasticizers, articles, and methods of making and using the same | 3M创新有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-109153799-B | Oriented polylactic acid polymer-based film | 3M创新有限公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-110062791-B | Compositions and films comprising polylactic acid polymers and copolymers comprising long chain alkyl moieties | 3M创新有限公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-113614152-A | Films comprising polylactic acid polymers suitable for graphic articles | 3M创新有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-113549246-A | Hyperbranched microcrystalline nucleating agent composition and application thereof | 中化石化销售有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-113444343-A | Preparation method of hyperbranched microcrystalline nucleating agent and preparation method of polyolefin resin | 中化石化销售有限公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-109312147-B | Graphic article comprising semicrystalline polylactic acid-based film | 3M创新有限公司 | 2021-04-16 | — | — | CN | disclosed |
| CN-108779370-B | Packaged pre-adhesive composition, adhesive and article comprising polylactic acid containing packaging material | 3M创新有限公司 | 2021-02-12 | — | — | CN | disclosed |
| CN-104053535-A | Polyester film and manufacturing process therefor | TORAY INDUSTRIES | 2014-09-17 | — | — | CN | disclosed |
| EP-1717267-B1 | Resin composition and molded product obtained therefrom | SONY CORP (JP) | 2008-05-14 | — | — | EP | disclosed |
| EP-1717267-A1 | Resin composition and molded product obtained therefrom | SONY CORPORATION (JP) | 2006-11-02 | — | — | EP | disclosed |
| US-4258142-A | ADDING A PHENYL PHOSPHATE AND METAL COMPOUND | ARGUS CHEMICAL CORP. (US) | 1981-03-24 | — | — | US | disclosed |