SCHEMBL18495641

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2648750	0.83	PIK3CA (0.46)	CLK1TDP1ALDH1A1HIF1ACDK2
	SCHEMBL31119106	0.83	PIK3CA (0.46)	CLK1TDP1ALDH1A1HIF1ACDK2
	SCHEMBL20265102	0.81	CLK1 (0.60)	CLK1CDC7ROCK1GSK3BCDK5
	SCHEMBL18495643	0.77	FEN1 (0.48)	CLK1CDC7GSK3BCDK5CDK5R1
	SCHEMBL4526945	0.76	ROCK1 (0.57)	CLK1CDC7ROCK1ALDH1A1PIK3CA
	SCHEMBL30775416	0.76	MAP3K14 (0.57)	CDC7ROCK1GSK3BCDK5CDK5R1
	SCHEMBL2658617	0.76	ALDH1A1 (0.45)	TDP1ALDH1A1HIF1AAMY1AMAPT
	SCHEMBL30369564	0.76	CLK1 (1.00)	CLK1GSK3BCDK5CDK5R1CDK2
	SCHEMBL30369770	0.76	CLK1 (0.82)	CLK1GSK3BCDK5CDK5R1MAP3K14
	SCHEMBL28982761	0.76	CLK1 (1.00)	CLK1GSK3BCDK5CDK5R1CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.