Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | UBE2N | P61088 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13335117 | 0.77 | KDM4E (0.35) | KDM4EUBE2NHTTMAPTLMNA | |
| SCHEMBL6453828 | 0.76 | ALDH1A1 (0.45) | KDM4EUBE2NALDH1A1IMPDH2POLB | |
| SCHEMBL15910207 | 0.72 | MAPT (0.42) | KDM4EUBE2NKMT2AMEN1HTT | |
| SCHEMBL19938115 | 0.70 | SMN1; SMN2 (0.35) | KDM4EUBE2NALDH1A1SMN1; SMN2HTT | |
| SCHEMBL946372 | 0.70 | KDM4E (1.00) | KDM4EUBE2NALDH1A1IMPDH2POLB | |
| SCHEMBL29694480 | 0.70 | KDM4E (1.00) | KDM4EUBE2NALDH1A1IMPDH2POLB | |
| SCHEMBL8758318 | 0.68 | ALDH1A1 (0.76) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL378958 | 0.68 | ALDH1A1 (1.00) | KDM4EUBE2NALDH1A1IMPDH2POLB | |
| SCHEMBL29365374 | 0.68 | ALDH1A1 (1.00) | KDM4EUBE2NALDH1A1IMPDH2POLB | |
| SCHEMBL28501014 | 0.67 | PTGS2 (0.67) | KDM4EUBE2NALDH1A1IMPDH2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567301-B2 | Pyrrol-1-yl benzoic acid derivatives useful as myc inhibitors | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-02-14 | — | — | US | disclosed |