Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 13/20 | 0.51 |
| ▸ | P2RY2 | P41231 | 11/20 | 0.51 |
| ▸ | P2RY4 | P51582 | 6/20 | 0.49 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | POLA1 | P09884 | 1/20 | 0.45 |
| ▸ | POLD1 | P28340 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17198444 | 0.93 | P2RY6 (0.53) | P2RY6P2RY2P2RY4P2RY14NT5E | |
| SCHEMBL18503431 | 0.91 | POLB (0.55) | P2RY6P2RY2P2RY4POLBPOLA1 | |
| SCHEMBL18503414 | 0.85 | P2RY2 (0.65) | P2RY6P2RY2P2RY4P2RY14 | |
| SCHEMBL18512680 | 0.84 | POLB (0.55) | P2RY6P2RY2P2RY4POLBPOLA1 | |
| SCHEMBL18503446 | 0.83 | LMNA (0.47) | P2RY6P2RY14NT5E | |
| SCHEMBL148675 | 0.81 | P2RY6 (0.73) | P2RY6P2RY2P2RY4P2RY14NT5E | |
| SCHEMBL148676 | 0.81 | P2RY6 (0.73) | P2RY6P2RY2P2RY4P2RY14NT5E | |
| SCHEMBL26883024 | 0.80 | DNPH1 (0.62) | P2RY6P2RY2P2RY4 | |
| SCHEMBL26883176 | 0.80 | DNPH1 (0.62) | P2RY6P2RY2P2RY4 | |
| SCHEMBL31381451 | 0.80 | DNPH1 (0.62) | P2RY6P2RY2P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044205-A1 | 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES NUCLEOTIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS, INC. | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044205-A1 | 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES NUCLEOTIDES FOR THE TREATMENT OF HCV | RB1, NSUN2, METTL3 | P2RY6 821/4885P2RY2 390/4885P2RY4 820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.