Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784858 | 0.85 | ALDH1A1 (0.44) | KMT2AKDM4EMEN1GAAMAPT | |
| SCHEMBL821094 | 0.80 | ALDH1A1 (0.54) | KMT2AMEN1GAAMAPTTDP1 | |
| SCHEMBL26064904 | 0.79 | CA12 (0.41) | KMT2AKDM4EMEN1GAAMAPT | |
| SCHEMBL11051 | 0.79 | CA12 (0.53) | KMT2AKDM4EMEN1GAAMAPT | |
| SCHEMBL16371883 | 0.79 | CA12 (0.53) | KMT2AKDM4EMEN1GAAMAPT | |
| Hydrochloric Acid SCHEMBL728400 | 0.77 | CA12 (0.52) | KMT2AKDM4EMEN1GAAMAPT | |
| SCHEMBL10385905 | 0.77 | CA12 (0.52) | KMT2AKDM4EMEN1GAAMAPT | |
| SCHEMBL253353 | 0.77 | CA12 (0.52) | KMT2AKDM4EMEN1GAAMAPT | |
| Water SCHEMBL10657216 | 0.77 | CA12 (0.52) | KMT2AKDM4EMEN1GAAMAPT | |
| SCHEMBL28296540 | 0.77 | CA12 (0.52) | KMT2AKDM4EMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1741772-B1 | Use of lubricating oil compositions for EGR equipped diesel engines | INFINEUM INT LTD (GB) | 2018-09-12 | — | — | EP | claimed |
| EP-1976821-B1 | DIRECT ALKYLATION OF N-ALKYL-N'-PHENYL-P-PHENYLENEDIAMINE | CHEMTURA CORP (US) | 2011-05-25 | — | — | EP | claimed |
| EP-1976821-A1 | DIRECT ALKYLATION OF N-ALKYL-N'-PHENYL-P-PHENYLENEDIAMINE | CHEMTURA CORPORATION (US) | 2008-10-08 | — | — | EP | claimed |
| US-7361788-B2 | Direct alkylation of N-alkyl-N′-phenyl-p-phenylenediamine | CHEMTURA CORPORATION (US) | 2008-04-22 | — | — | US | claimed |
| WO-2007087195-A1 | DIRECT ALKYLATION OF N-ALKYL-N'-PHENYL-P-PHENYLENEDIAMINE | CHEMTURA CORPORATION (US) | 2007-08-02 | — | — | WO | claimed |
| US-20070173668-A1 | Direct alkylation of N-alkyl-N'-phenyl-p-phenylenediamine | LANXESS SOLUTIONS US INC. | 2007-07-26 | — | — | US | claimed |
| CN-107109282-B | Lubricating composition with seal compatibility | 路博润公司 | 2020-03-27 | — | — | CN | disclosed |
| EP-1741772-B1 | Use of lubricating oil compositions for EGR equipped diesel engines | INFINEUM INT LTD (GB) | 2018-09-12 | — | — | EP | disclosed |
| US-8741824-B2 | EGR equipped diesel engines and lubricating oil compositions | INFINEUM INTERNATIONAL LIMITED (GB) | 2014-06-03 | — | — | US | disclosed |
| EP-1976821-B1 | DIRECT ALKYLATION OF N-ALKYL-N'-PHENYL-P-PHENYLENEDIAMINE | CHEMTURA CORP (US) | 2011-05-25 | — | — | EP | disclosed |
| EP-1976821-B1 | DIRECT ALKYLATION OF N-ALKYL-N'-PHENYL-P-PHENYLENEDIAMINE | CHEMTURA CORP (US) | 2011-05-25 | — | — | EP | disclosed |
| CN-101370766-A | Direct alkylation of N-alkyl-N'-phenyl-p-phenylenediamine | CHEMTURA CORP (US) | 2009-02-18 | — | — | CN | disclosed |
| EP-1976821-A1 | DIRECT ALKYLATION OF N-ALKYL-N'-PHENYL-P-PHENYLENEDIAMINE | CHEMTURA CORPORATION (US) | 2008-10-08 | — | — | EP | disclosed |
| EP-1741772-A2 | Lubricating oil compositions for EGR equipped diesel engines and methods of lubrication | Infineum International Limited (GB) | 2007-01-10 | — | — | EP | disclosed |
| US-5344861-A | Polymer blend with organic acid, phenylamine, phenylenediamine and acid acceptor with vulcanization agent | TOSOH CORPORATION (JP) | 1994-09-06 | — | — | US | disclosed |
| US-5068438-A | Granulation and rotation with heat treatment to form free-flowing particles | MITSUBISHI MONSANTO CHEMICAL COMPANY (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0138732-B1 | A PROCESS FOR THE REDUCTIVE ALKYLATION OF AROMATIC NITRO-CONTAINING COMPOUNDS WITH KETONES OR ALDEHYDES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-01-07 | — | — | EP | disclosed |
| US-4463191-A | ONE STEP USING CATALYSTS OF ANTHRANILIC ACID- AND PALLADIUM-MODIFIED POLYMER AND A SULFONIC ACID RESIN | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1984-07-31 | — | — | US | disclosed |
| US-4051067-A | Stabilization of unsaturated carboxylic acid esters with mixtures of polyalkyleneamines and arylenediamines | MONSANTO COMPANY (US) | 1977-09-27 | — | — | US | disclosed |
| US-4016198-A | Stabilization of unsaturated carboxylic acid esters with mixtures of polyalkylene-amines and arylenediamines | MONSANTO COMPANY (US) | 1977-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173668-A1 | Direct alkylation of N-alkyl-N'-phenyl-p-phenylenediamine | PNMT, AAAS, PNN | KMT2A 281/4885KDM4E 736/4885MEN1 2280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.