Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2530355 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2AALDH1A1PMP22TP53 | |
| SCHEMBL10883918 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2AALDH1A1PMP22TP53 | |
| SCHEMBL9275302 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2AALDH1A1PMP22TP53 | |
| SCHEMBL63155 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2AALDH1A1PMP22TP53 | |
| SCHEMBL10927483 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2AALDH1A1PMP22TP53 | |
| SCHEMBL7893576 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2AALDH1A1PMP22TP53 | |
| SCHEMBL63154 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2AALDH1A1PMP22TP53 | |
| SCHEMBL10883899 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2AALDH1A1PMP22TP53 | |
| SCHEMBL18503560 | 0.91 | LMNA (0.59) | ALDH1A1PMP22TSHRNFKB1NPC1 | |
| SCHEMBL1572862 | 0.89 | ADORA3 (0.49) | ADORA3ADORA2AALDH1A1PMP22TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044619-A1 | PROFILING CHEMICALLY MODIFIED DNA/RNA UNITS FOR DISEASE AND CANCER DIAGNOSIS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2017-02-16 | — | — | US | disclosed |