SCHEMBL63154

SCHEMBL63154

CC(O)C(NC(=O)Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ADORA3 P0DMS8 2/20 0.59
▸ ADORA2A P29274 2/20 0.59
▸ ALDH1A1 P00352 2/20 0.59
▸ PMP22 Q01453 2/20 0.59
▸ TP53 P04637 1/20 0.59
▸ CYP3A4 P08684 1/20 0.59
▸ TSHR P16473 1/20 0.59
▸ ALOX12 P18054 1/20 0.59
▸ NFKB1 P19838 1/20 0.59
▸ HIF1A Q16665 1/20 0.59
▸ HPGD P15428 1/20 0.59
▸ NPC1 O15118 1/20 0.59
▸ ADORA2B P29275 1/20 0.59
▸ ADORA1 P30542 1/20 0.59
▸ RAB9A P51151 1/20 0.59
▸ RXFP1 Q9HBX9 1/20 0.59
▸ LMNA P02545 1/20 0.58
▸ GLA P06280 1/20 0.58
▸ SMN1; SMN2 Q16637 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2530355 1.00 ADORA3 (0.59) ADORA3ADORA2AALDH1A1PMP22TP53
SCHEMBL10883918 1.00 ADORA3 (0.59) ADORA3ADORA2AALDH1A1PMP22TP53
SCHEMBL9275302 1.00 ADORA3 (0.59) ADORA3ADORA2AALDH1A1PMP22TP53
SCHEMBL63155 1.00 ADORA3 (0.59) ADORA3ADORA2AALDH1A1PMP22TP53
SCHEMBL10927483 1.00 ADORA3 (0.59) ADORA3ADORA2AALDH1A1PMP22TP53
SCHEMBL7893576 1.00 ADORA3 (0.59) ADORA3ADORA2AALDH1A1PMP22TP53
SCHEMBL10883899 1.00 ADORA3 (0.59) ADORA3ADORA2AALDH1A1PMP22TP53
SCHEMBL18503542 1.00 ADORA3 (0.59) ADORA3ADORA2AALDH1A1PMP22TP53
SCHEMBL18503560 0.91 LMNA (0.59) ALDH1A1PMP22TSHRNFKB1NPC1
SCHEMBL1572862 0.89 ADORA3 (0.49) ADORA3ADORA2AALDH1A1PMP22TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 478 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2640852-A1 SIGNAL AMPLIFICATION Speedx Pty Ltd (AU) 2013-09-25 — — EP claimed
US-8394946-B2 Multicomponent nucleic acid enzymes and methods for their use SPEEDX PTY LTD (AU) 2013-03-12 — — US claimed
WO-2012065231-A1 SIGNAL AMPLIFICATION SPEEDX PTY LTD (AU) 2012-05-24 — — WO claimed
CN-101341260-A Multi-component nucleases and methods of use thereof JOHNSON & JOHNSON RES PTY LTD (AU) 2009-01-07 — — CN claimed
EP-1948822-A1 MULTICOMPONENT NUCLEIC ACID ENZYMES AND METHODS FOR THEIR USE JOHNSON & JOHNSON RESEARCH PTY LIMITED (AU) 2008-07-30 — — EP claimed
US-20070231810-A1 Multicomponent nucleic acid enzymes and methods for their use SPEEDX PTY LTD (AU) 2007-10-04 — — US claimed
WO-2007041774-A1 MULTICOMPONENT NUCLEIC ACID ENZYMES AND METHODS FOR THEIR USE JOHNSON & JOHNSON RESEARCH PTY LIMITED (AU) 2007-04-19 — — WO claimed
EP-0795029-A1 CHEMICAL LABELLING OF OBJECTS Pabio (NO) 1997-09-17 — — EP claimed
WO-1996017954-A1 CHEMICAL LABELLING OF OBJECTS PABIO (DK) 1996-06-13 — — WO claimed
WO-2026102473-A1 TEMPERATURE DEPENDENT PROBES FOR TARGET DETECTION SPEEDX PTY LTD (AU) 2026-05-21 — — WO disclosed
EP-4731186-A2 METHODS AND COMPOSITIONS FOR TREATING EPITHELIAL DISEASES The Regents of the University of California (US) 2026-04-29 — — EP disclosed
US-20260097121-A1 Biallelic Knockout of CISH EMENDOBIO INC (US) 2026-04-09 — — US disclosed
US-20260097123-A1 Biallelic Knockout of CIITA EMENDOBIO INC (US) 2026-04-09 — — US disclosed
US-20260085331-A1 Biallelic Knockout of PDCD1 EMENDOBIO INC (US) 2026-03-26 — — US disclosed
US-6004754-A METHODS AND NUCLEIC ACID SEQUENCES FOR IDENTIFYING STREPTOCOCCUS AGALACTIAE BY NUCLEIC ACID AMPLIFICATION AND NUCLEIC ACID HYBRIDIZATION BECTON DICKINSON AND COMPANY (US) 1999-12-21 — — US disclosed
EP-0905259-A1 Identification of a DNA region potentially useful for the detection of mycobacterium kansasii Becton, Dickinson and Company (US) 1999-03-31 — — EP disclosed
US-5821052-A BINDS TO COMPLEMENTARY BASES OF TRANSFER RNA; INHIBITS TRANSLATION OF THE PROTEIN; FOR USE IN BACTERIA OR CELL-FREE SYSTEMS TO CONTROL SYNTHESIS OF A PROTEIN UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) 1998-10-13 — — US disclosed
EP-0795029-A1 CHEMICAL LABELLING OF OBJECTS Pabio (NO) 1997-09-17 — — EP disclosed
WO-1996017954-A1 CHEMICAL LABELLING OF OBJECTS PABIO (DK) 1996-06-13 — — WO disclosed
US-5258284-A Nucleic acid probes specific for pathogenic strains of vibrio vulnificus and method employing the same UNIVERSITY OF MARYLAND, SCHOOL OF MEDICINE (US) 1993-11-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097121-A1 Biallelic Knockout of CISH PBK, ZFP3, ZFR ADORA3 3049/4885ADORA2A 4371/4885ALDH1A1 3614/4885
US-20260097123-A1 Biallelic Knockout of CIITA IKZF1, IKZF3, PRDM9 ADORA3 2007/4885ADORA2A 3251/4885ALDH1A1 2571/4885
US-20260085331-A1 Biallelic Knockout of PDCD1 PDCD1, STING1, PBK ADORA3 2284/4885ADORA2A 3578/4885ALDH1A1 2066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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