Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10883918 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2AALDH1A1PMP22TP53 | |
| SCHEMBL9275302 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2AALDH1A1PMP22TP53 | |
| SCHEMBL63155 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2AALDH1A1PMP22TP53 | |
| SCHEMBL10927483 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2AALDH1A1PMP22TP53 | |
| SCHEMBL7893576 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2AALDH1A1PMP22TP53 | |
| SCHEMBL63154 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2AALDH1A1PMP22TP53 | |
| SCHEMBL10883899 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2AALDH1A1PMP22TP53 | |
| SCHEMBL18503542 | 1.00 | ADORA3 (0.59) | ADORA3ADORA2AALDH1A1PMP22TP53 | |
| SCHEMBL18503560 | 0.91 | LMNA (0.59) | ALDH1A1PMP22TSHRNFKB1NPC1 | |
| SCHEMBL1572862 | 0.89 | ADORA3 (0.49) | ADORA3ADORA2AALDH1A1PMP22TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877449-B2 | Method for obtaining pancreatic progenitor cell using NEPH3 | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2014-11-04 | — | — | US | disclosed |
| US-20110256548-A1 | METHOD FOR OBTAINING PANCREATIC PROGENITOR CELL USING NEPH3 | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-10-20 | — | — | US | disclosed |
| EP-1161560-A1 | ELECTROPOLYMERIZABLE FILM, AND METHOD OF MAKING AND USE THEREOF | The University of North Carolina at Chapel Hill (US) | 2001-12-12 | — | — | EP | disclosed |
| US-6180346-B1 | ELECTROCHEMICAL DETECTION OF NUCLEIC ACIDS | THE UNIVERSTIY OF NORTH CAROLINA AT CHAPEL HILL | 2001-01-30 | — | — | US | disclosed |
| WO-2000055366-A1 | ELECTROPOLYMERIZABLE FILM, AND METHOD OF MAKING AND USE THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2000-09-21 | — | — | WO | disclosed |
| US-5968745-A | ELECTRODE OF SUBSTRATE HAVING ELECTROCONDUCTIVE WORKING SURFACE AND A NONCONDUCTIVE OUTER POLYMER LAYER WHERE PROBES CAN BE ATTACHED HAVING MICROFLUIDIC REACTION OPENINGS FOR TRANSITION METAL COMPLEX TO TRANSFER ELECTRONS TO SURFACE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1999-10-19 | — | — | US | disclosed |