Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 4/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | MARK3 | P27448 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ULK1 | O75385 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18503624 | 0.92 | HDAC6 (0.44) | HDAC6MAPTHCRTR1HCRTR2SUCNR1 | |
| SCHEMBL18503592 | 0.90 | HDAC6 (0.42) | HDAC6CNR2 | |
| SCHEMBL18503627 | 0.89 | HDAC6 (0.43) | HDAC6HCRTR1HCRTR2SCN9ACFTR | |
| SCHEMBL17713159 | 0.89 | HDAC6 (0.46) | HDAC6SUCNR1TRPV1CFTRGLA | |
| SCHEMBL18503636 | 0.88 | HDAC6 (0.44) | HDAC6HCRTR1HCRTR2SUCNR1SCN9A | |
| SCHEMBL18503614 | 0.88 | LMNA (0.41) | SCN9ADYRK1ALMNA | |
| SCHEMBL18503632 | 0.87 | HDAC6 (0.44) | HDAC6HCRTR1HCRTR2SUCNR1TRPV1 | |
| SCHEMBL18503620 | 0.87 | HDAC6 (0.42) | HDAC6HCRTR1HCRTR2SUCNR1TRPV1 | |
| SCHEMBL19566560 | 0.86 | HDAC6 (0.45) | HDAC6SUCNR1LMNACNR2 | |
| SCHEMBL18503621 | 0.84 | HDAC6 (0.42) | HDAC6HCRTR1HCRTR2DYRK1ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | ACHE, DDT, DNPH1 | HDAC6 150/4885MAPT 3764/4885HCRTR1 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.