Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 12/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16771887 | 0.91 | HDAC6 (0.43) | HDAC6P2RX7CNR2CYP1A2CYP2C9 | |
| SCHEMBL18512984 | 0.91 | HDAC6 (0.41) | HDAC6P2RX7CYP11B2NTRK1 | |
| SCHEMBL18503624 | 0.90 | HDAC6 (0.44) | HDAC6P2RX7CYP11B2CNR2 | |
| SCHEMBL18503622 | 0.90 | HDAC6 (0.44) | HDAC6CNR2 | |
| SCHEMBL16552222 | 0.90 | HDAC6 (0.43) | HDAC6P2RX7CNR2CYP1A2CYP2C9 | |
| SCHEMBL19566553 | 0.89 | HDAC6 (0.44) | HDAC6P2RX7NTRK1CNR2CYP1A2 | |
| SCHEMBL19566548 | 0.88 | HDAC6 (0.45) | HDAC6P2RX7CNR2CYP1A2CYP2C9 | |
| SCHEMBL16760327 | 0.87 | P2RX7 (0.40) | P2RX7CYP11B2 | |
| SCHEMBL18503628 | 0.85 | HDAC6 (0.42) | HDAC6P2RX7CNR2CYP1A2CYP2C9 | |
| SCHEMBL17917775 | 0.84 | HDAC6 (0.42) | HDAC6P2RX7NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044104-A1 | NEW PESTICIDAL COMPOUNDS AND USES | ACHE, DDT, DNPH1 | HDAC6 150/4885P2RX7 74/4885CYP11B2 2963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.