Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14764011 | 0.82 | ALDH1A1 (0.36) | LMNACYP3A4ALOX15NPC1ALDH1A1 | |
| SCHEMBL309490 | 0.81 | LMNA (0.39) | LMNACYP3A4ALOX15NPC1ALDH1A1 | |
| SCHEMBL18503906 | 0.81 | NPC1 (0.36) | LMNACYP3A4ALOX15NPC1ALDH1A1 | |
| SCHEMBL17204124 | 0.77 | TSHR (0.44) | LMNACYP3A4ALOX15NPC1ALDH1A1 | |
| SCHEMBL17213211 | 0.77 | TSHR (0.44) | LMNACYP3A4ALOX15NPC1ALDH1A1 | |
| SCHEMBL18513491 | 0.77 | TSHR (0.44) | LMNACYP3A4ALOX15NPC1ALDH1A1 | |
| SCHEMBL2441097 | 0.73 | LMNA (0.45) | LMNACYP3A4ALOX15NPC1ALDH1A1 | |
| SCHEMBL12032240 | 0.73 | LMNA (0.39) | LMNACYP3A4ALOX15NPC1ALDH1A1 | |
| SCHEMBL21822060 | 0.72 | LMNA (0.36) | LMNACYP3A4ALOX15NPC1ALDH1A1 | |
| SCHEMBL2443192 | 0.72 | LMNA (0.39) | LMNACYP3A4ALOX15NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044282-A1 | TERPENE AND TERPENOID DERIVATIVES CONTAINING VINYL GROUPS FOR THE PREPARATION OF POLYMERS | THE UNIVERSITY OF NOTTINGHAM (GB) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044282-A1 | TERPENE AND TERPENOID DERIVATIVES CONTAINING VINYL GROUPS FOR THE PREPARATION OF POLYMERS | GGPS1, DHPS, FDPS | LMNA 2028/4885CYP3A4 9/4885ALOX15 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.