Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | CD38 | P28907 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.34 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.34 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18504604 | 0.89 | GABRA5 (0.39) | STIM1ORAI1 | |
| SCHEMBL18504494 | 0.88 | STIM1 (0.34) | CD38STIM1ORAI1 | |
| SCHEMBL18504372 | 0.88 | STIM1 (0.34) | STIM1ORAI1 | |
| SCHEMBL22564271 | 0.87 | AURKA (0.36) | AURKARPS6KB1AURKBCD38CYP3A4 | |
| SCHEMBL18504947 | 0.86 | RORC (0.38) | KDM4ESTIM1ORAI1 | |
| SCHEMBL18504784 | 0.86 | LMNA (0.46) | KDM4ESMN1; SMN2STIM1ORAI1 | |
| SCHEMBL18504440 | 0.85 | STIM1 (0.36) | CD38STIM1ORAI1 | |
| SCHEMBL18504408 | 0.84 | HSD17B10 (0.43) | CYP3A4KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL18504774 | 0.84 | KLKB1 (0.37) | AURKARPS6KB1CD38MAOBPARP1 | |
| SCHEMBL18504727 | 0.84 | SCN9A (0.41) | CYP3A4SCN9ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9565856-B2 | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-14 | — | — | US | disclosed |