Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STIM1 | Q13586 | 1/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 3/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.33 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.32 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.32 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18504784 | 0.90 | LMNA (0.46) | STIM1ORAI1POLBRXFP1TP53 | |
| SCHEMBL22564404 | 0.88 | STIM1 (0.36) | STIM1ORAI1POLBRXFP1TP53 | |
| SCHEMBL18504372 | 0.88 | STIM1 (0.34) | STIM1ORAI1POLBRXFP1TP53 | |
| SCHEMBL18504604 | 0.86 | GABRA5 (0.39) | STIM1ORAI1GABRA5MRGPRX4 | |
| SCHEMBL18504947 | 0.86 | RORC (0.38) | STIM1ORAI1POLBTP53KCNK3 | |
| SCHEMBL18504751 | 0.85 | SGMS2 (0.37) | SGMS2GUCY1B2GUCY1A2GUCY1A1GUCY1B1 | |
| SCHEMBL18504416 | 0.85 | AURKA (0.37) | STIM1ORAI1CD38 | |
| SCHEMBL18504494 | 0.85 | STIM1 (0.34) | STIM1ORAI1POLBRXFP1LMNA | |
| SCHEMBL18504801 | 0.85 | KCNK3 (0.35) | RXFP1TP53KCNK3KCNK9GUCY1B2 | |
| SCHEMBL18504643 | 0.84 | FFAR4 (0.32) | RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9565856-B2 | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-14 | — | — | US | disclosed |