Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GUCY1B2 | O75343 | 7/20 | 0.34 |
| ▸ | GUCY1A2 | P33402 | 7/20 | 0.34 |
| ▸ | GUCY1A1 | Q02108 | 7/20 | 0.34 |
| ▸ | GUCY1B1 | Q02153 | 7/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | LIG1 | P18858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18504744 | 0.91 | SGMS2 (0.36) | SGMS2TDP1GUCY1B2GUCY1A2GUCY1A1 | |
| SCHEMBL18504751 | 0.89 | SGMS2 (0.37) | SGMS2TDP1GUCY1B2GUCY1A2GUCY1A1 | |
| SCHEMBL22564169 | 0.87 | HDAC1 (0.35) | HDAC1HDAC6SGMS2TDP1GUCY1B2 | |
| SCHEMBL18504583 | 0.87 | ALDH1A1 (0.33) | TDP1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL18500953 | 0.86 | ALKBH1 (0.40) | SGMS2TDP1NPC1ALKBH1KMT2A | |
| SCHEMBL18504779 | 0.86 | PDE5A (0.32) | HDAC1HDAC6LMNAPDE5ALIG1 | |
| SCHEMBL18504821 | 0.86 | HDAC3 (0.41) | HDAC1HDAC6SGMS2NPC1MEN1 | |
| SCHEMBL18504787 | 0.86 | HDAC3 (0.41) | HDAC1HDAC6SGMS2TDP1KMT2A | |
| SCHEMBL18504646 | 0.86 | PDE5A (0.35) | HDAC1HDAC6PDE5ALIG1 | |
| SCHEMBL18504220 | 0.86 | KMT2A (0.40) | TDP1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9565856-B2 | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-14 | — | — | US | disclosed |