Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21722997 | 0.82 | — | — | |
| SCHEMBL3829492 | 0.81 | MAPT (0.39) | ALDH1A1DPP4MAPTGAA | |
| SCHEMBL25975361 | 0.79 | DPP4 (0.34) | ALDH1A1DPP4GAA | |
| SCHEMBL23298052 | 0.77 | CHRNB2 (0.31) | — | |
| SCHEMBL18218802 | 0.76 | — | — | |
| SCHEMBL14407039 | 0.76 | SLC6A12 (0.40) | ALDH1A1MAPT | |
| SCHEMBL3077368 | 0.75 | ARG1 (0.33) | — | |
| SCHEMBL16399328 | 0.73 | — | — | |
| SCHEMBL2000136 | 0.72 | LTA4H (0.31) | — | |
| SCHEMBL15285886 | 0.72 | BRD4 (0.50) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017027684-A1 | FUMAGILLOL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME | ZAFGEN, INC. (US) | 2017-02-16 | — | — | WO | disclosed |