Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK2 | P53671 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.46 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | PDE6D | O43924 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15497755 | 0.87 | SMN1; SMN2 (0.43) | LIMK2BRD4NR3C1P2RX7KCNH2 | |
| SCHEMBL5981532 | 0.85 | LIMK2 (0.63) | LIMK2HSD17B10BRD4MEN1KMT2A | |
| SCHEMBL17621 | 0.85 | HSD17B10 (0.62) | LIMK2HSD17B10BRD4MEN1KMT2A | |
| SCHEMBL2840217 | 0.83 | LIMK2 (0.58) | LIMK2HSD17B10BRD4MEN1KMT2A | |
| Bromide SCHEMBL811908 | 0.83 | HSD17B10 (0.60) | LIMK2HSD17B10BRD4MEN1KMT2A | |
| Fluoride SCHEMBL10339918 | 0.83 | HSD17B10 (0.60) | LIMK2HSD17B10BRD4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL233781 | 0.83 | HSD17B10 (0.60) | LIMK2HSD17B10BRD4MEN1KMT2A | |
| Iodide SCHEMBL28519464 | 0.83 | HSD17B10 (0.60) | LIMK2HSD17B10BRD4MEN1KMT2A | |
| SCHEMBL9164995 | 0.83 | KIF11 (0.51) | LIMK2BRD4KIF11 | |
| SCHEMBL10906967 | 0.82 | LIMK2 (0.56) | LIMK2HSD17B10BRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016057658-A9 | PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | MITOBRIDGE, INC. (US) | 2017-02-16 | — | — | WO | disclosed |