Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.67 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.67 |
| ▸ | NQO2 | P16083 | 1/20 | 0.67 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.67 |
| ▸ | PPARG | P37231 | 2/20 | 0.65 |
| ▸ | PPARD | Q03181 | 2/20 | 0.65 |
| ▸ | PPARA | Q07869 | 2/20 | 0.65 |
| ▸ | HTR6 | P50406 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19872723 | 0.89 | POLB (0.56) | MTNR1AMTNR1BNQO2ADRB2PPARG | |
| SCHEMBL15242222 | 0.88 | MTNR1A (0.70) | MTNR1AMTNR1BNQO2ADRB2PPARG | |
| SCHEMBL2685182 | 0.86 | MTNR1A (0.63) | MTNR1AMTNR1BNQO2ADRB2HTR6 | |
| SCHEMBL8306890 | 0.83 | ADRB2 (0.74) | MTNR1AMTNR1BNQO2ADRB2HTR6 | |
| SCHEMBL20119843 | 0.82 | SPR (0.60) | MTNR1AMTNR1BNQO2PPARGPPARD | |
| SCHEMBL18509793 | 0.82 | TP53 (0.53) | MTNR1AMTNR1BNQO2ADRB2PPARG | |
| SCHEMBL12185393 | 0.81 | ADRB2 (0.76) | MTNR1AMTNR1BNQO2ADRB2HTR6 | |
| SCHEMBL13888101 | 0.81 | ADRB2 (0.70) | MTNR1AMTNR1BNQO2ADRB2HTR6 | |
| SCHEMBL18509874 | 0.81 | HPGD (0.51) | MTNR1AMTNR1BNQO2ADRB2PPARG | |
| SCHEMBL18509694 | 0.81 | LMNA (0.49) | MTNR1AMTNR1BNQO2ADRB2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078467-B2 | Highly active self-sufficient nitration biocatalysts | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-08-03 | — | — | US | disclosed |
| US-10550079-B2 | Artificial self-sufficient cytochrome P450s | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2020-02-04 | — | — | US | disclosed |
| US-20190292527-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-09-26 | — | — | US | disclosed |
| US-20190119208-A1 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-04-25 | — | — | US | disclosed |
| WO-2018081456-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-05-03 | — | — | WO | disclosed |
| US-20180044291-A1 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2018-02-15 | — | — | US | disclosed |
| WO-2016134145-A9 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2017-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078467-B2 | Highly active self-sufficient nitration biocatalysts | POR, CYP4F3, CBR3 | MTNR1A 3563/4885MTNR1B 4196/4885NQO2 150/4885 |
| US-20180044291-A1 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | CYP4F2, POR, CYP4F3 | MTNR1A 2049/4885MTNR1B 2814/4885NQO2 126/4885 |
| US-20190292527-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | POR, CYP4F3, CBR3 | MTNR1A 3563/4885MTNR1B 4196/4885NQO2 150/4885 |
| US-10550079-B2 | Artificial self-sufficient cytochrome P450s | CYP4F2, CYP2F1, POR | MTNR1A 2068/4885MTNR1B 2862/4885NQO2 136/4885 |
| US-20190119208-A1 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | CYP4F2, CYP2F1, POR | MTNR1A 2068/4885MTNR1B 2862/4885NQO2 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.