2-Methyladenosine

2-Methyladenosine

SCHEMBL18512844

Cc1nc(N)c2ncn([C@@H]3O[C@H](CO)[C@H](O)[C@@H]3O)c2n1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.75
NT5E P21589 1/20 0.75
HIF1A Q16665 1/20 0.75
ADORA2A P29274 7/20 0.74
ADORA2B P29275 5/20 0.74
ADORA3 P0DMS8 2/20 0.72
ADORA1 P30542 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Methyladenosine SCHEMBL41422 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL278664 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL17124834 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL41423 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL18159462 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL18512845 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL6934268 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL14075776 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL13403859 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL6725555 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023183569-A1 METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS Molecular Assemblies, Inc. (US) 2023-09-28 WO disclosed
US-11339441-B2 Profiling chemically modified DNA/RNA units for disease and cancer diagnosis THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-05-24 US disclosed
US-20170044619-A1 PROFILING CHEMICALLY MODIFIED DNA/RNA UNITS FOR DISEASE AND CANCER DIAGNOSIS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK 2017-02-16 US disclosed