2-Methyladenosine

2-Methyladenosine

SCHEMBL18159462

Cc1nc(N)c2ncn([C@@H]3O[C@H](CO)[C@H](O)C3O)c2n1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.75
NT5E P21589 1/20 0.75
HIF1A Q16665 1/20 0.75
ADORA2A P29274 7/20 0.74
ADORA2B P29275 5/20 0.74
ADORA3 P0DMS8 2/20 0.72
ADORA1 P30542 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Methyladenosine SCHEMBL41422 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL278664 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL17124834 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL41423 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL18512844 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL18512845 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL6934268 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL14075776 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL13403859 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL6725555 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9771390-B2 Process for the preparation of regadenoson SCINOPHARM TAIWAN, LTD. (TW) 2017-09-26 US disclosed
US-20170044619-A1 PROFILING CHEMICALLY MODIFIED DNA/RNA UNITS FOR DISEASE AND CANCER DIAGNOSIS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK 2017-02-16 US disclosed
US-20160304551-A1 A PROCESS FOR THE PREPARATION OF REGADENOSON SCINOPHARM TAIWAN, LTD. (TW) 2016-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160304551-A1 A PROCESS FOR THE PREPARATION OF REGADENOSON PARP6, REV1, ARF6 LMNA 1097/4885NT5E 1928/4885HIF1A 1758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.