Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | NT5E | P21589 | 1/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.75 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.74 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.72 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Methyladenosine SCHEMBL41422 | 1.00 | LMNA (0.75) | LMNANT5EHIF1AADORA2AADORA2B | |
| 2-Methyladenosine SCHEMBL278664 | 1.00 | LMNA (0.75) | LMNANT5EHIF1AADORA2AADORA2B | |
| 2-Methyladenosine SCHEMBL14075776 | 1.00 | LMNA (0.75) | LMNANT5EHIF1AADORA2AADORA2B | |
| 2-Methyladenosine SCHEMBL41423 | 1.00 | LMNA (0.75) | LMNANT5EHIF1AADORA2AADORA2B | |
| 2-Methyladenosine SCHEMBL6934268 | 1.00 | LMNA (0.75) | LMNANT5EHIF1AADORA2AADORA2B | |
| 2-Methyladenosine SCHEMBL18512844 | 1.00 | LMNA (0.75) | LMNANT5EHIF1AADORA2AADORA2B | |
| 2-Methyladenosine SCHEMBL13403859 | 1.00 | LMNA (0.75) | LMNANT5EHIF1AADORA2AADORA2B | |
| 2-Methyladenosine SCHEMBL17124834 | 1.00 | LMNA (0.75) | LMNANT5EHIF1AADORA2AADORA2B | |
| 2-Methyladenosine SCHEMBL18159462 | 1.00 | LMNA (0.75) | LMNANT5EHIF1AADORA2AADORA2B | |
| 2-Methyladenosine SCHEMBL6725555 | 1.00 | LMNA (0.75) | LMNANT5EHIF1AADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230099822-A1 | MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION | UNIVERSITÄT BASEL (CH) | 2023-03-30 | — | — | US | disclosed |
| EP-4090969-A1 | MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION | Universität Basel (CH) | 2022-11-23 | — | — | EP | disclosed |
| US-11339441-B2 | Profiling chemically modified DNA/RNA units for disease and cancer diagnosis | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-05-24 | — | — | US | disclosed |
| EP-3889602-A1 | MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION | Universität Basel (CH) | 2021-10-06 | — | — | EP | disclosed |
| WO-2021144475-A1 | MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION | UNIVERSITÄT BASEL (CH) | 2021-07-22 | — | — | WO | disclosed |
| US-20210196723-A1 | Modulators of DUX4 for Regulation of Muscle Function | SONIC MASTER LTD (VG) | 2021-07-01 | — | — | US | disclosed |
| US-10933068-B2 | Modulators of DUX4 for regulation of muscle function | SONIC MASTER LIMITED (VG) | 2021-03-02 | — | — | US | disclosed |
| US-20190298727-A1 | MODULATORS OF DUX4 FOR REGULATION OF MUSCLE FUNCTION | SONIC MASTER LIMITED (VG) | 2019-10-03 | — | — | US | disclosed |
| US-20170044619-A1 | PROFILING CHEMICALLY MODIFIED DNA/RNA UNITS FOR DISEASE AND CANCER DIAGNOSIS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210196723-A1 | Modulators of DUX4 for Regulation of Muscle Function | DDX21, MBNL1, MECP2 | LMNA 1943/4885NT5E 3561/4885HIF1A 2591/4885 |
| US-10933068-B2 | Modulators of DUX4 for regulation of muscle function | DDX21, MBNL1, MECP2 | LMNA 2031/4885NT5E 3565/4885HIF1A 2588/4885 |
| US-20230099822-A1 | MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION | MRGPRX1, MRGPRX2, CD47 | LMNA 3782/4885NT5E 804/4885HIF1A 2036/4885 |
| US-20190298727-A1 | MODULATORS OF DUX4 FOR REGULATION OF MUSCLE FUNCTION | DDX21, MBNL1, MECP2 | LMNA 2031/4885NT5E 3565/4885HIF1A 2588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.