2-Methyladenosine

2-Methyladenosine

SCHEMBL41423

Cc1nc(N)c2ncn([C@@H]3O[C@H](CO)C(O)C3O)c2n1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.75
NT5E P21589 1/20 0.75
HIF1A Q16665 1/20 0.75
ADORA2A P29274 7/20 0.74
ADORA2B P29275 5/20 0.74
ADORA3 P0DMS8 2/20 0.72
ADORA1 P30542 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Methyladenosine SCHEMBL41422 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL278664 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL17124834 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL18512844 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL18159462 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL18512845 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL6934268 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL14075776 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL13403859 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL6725555 1.00 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5593 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705481-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2026-03-11 EP claimed
EP-4705468-A1 MAMMALIAN POLYCISTRONIC EXPRESSION SYSTEM FOR DIRECT TRANSLATION FROM RNA AND SECRETION OF CARGO California Institute of Technology (US) 2026-03-11 EP claimed
EP-4632075-A2 METHOD FOR REDUCING IMMUNOGENICITY OF RNA BioNTech SE (DE) 2025-10-15 EP claimed
US-20250304965-A1 DOUBLE-STRANDED RNA MOLECULE AND PHARMACEUTICAL USE THEREOF MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2025-10-02 US claimed
EP-4029522-B1 METHOD FOR REDUCING IMMUNOGENICITY OF RNA BioNTech SE (DE) 2025-08-13 EP claimed
WO-2024233308-A2 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. (US) 2024-11-14 WO claimed
US-20240366793-A1 MAMMALIAN POLYCISTRONIC EXPRESSION SYSTEM FOR DIRECT TRANSLATION FROM RNA AND SECRETION OF CARGO CALIFORNIA INST OF TECHN (US) 2024-11-07 US claimed
WO-2024229296-A1 MAMMALIAN POLYCISTRONIC EXPRESSION SYSTEM FOR DIRECT TRANSLATION FROM RNA AND SECRETION OF CARGO CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2024-11-07 WO claimed
CN-118773192-A Oligonucleotide and composition thereof 力赛新(广东)制药有限公司 2024-10-15 CN claimed
US-20240229075-A1 IMPROVED NUCLEIC ACID SEQUENCE FOR CELL TYPE SPECIFIC EXPRESSION CureVac SE (DE) 2024-07-11 US claimed
CN-101316606-A Methods and pharmaceutical compositions for treating and preventing hepatitis C infection SCYNEXIS INC (US) 2008-12-03 CN claimed
EP-1948822-A1 MULTICOMPONENT NUCLEIC ACID ENZYMES AND METHODS FOR THEIR USE JOHNSON & JOHNSON RESEARCH PTY LIMITED (AU) 2008-07-30 EP claimed
US-20070231810-A1 Multicomponent nucleic acid enzymes and methods for their use SPEEDX PTY LTD (AU) 2007-10-04 US claimed
WO-2007041774-A1 MULTICOMPONENT NUCLEIC ACID ENZYMES AND METHODS FOR THEIR USE JOHNSON & JOHNSON RESEARCH PTY LIMITED (AU) 2007-04-19 WO claimed
EP-1539188-A2 NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RNA-DEPENDENT RNA VIRAL POLYMERASE Merck & Co., Inc. (US) 2005-06-15 EP claimed
US-20030007961-A1 Orthomolecular vitamin E derivatives WILBURN MICHAEL D (US) 2003-01-09 US claimed
WO-2002057425-A2 NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RNA-DEPENDENT RNA VIRAL POLYMERASE MERCK & CO., INC. (US) 2002-07-25 WO claimed
EP-0795029-A1 CHEMICAL LABELLING OF OBJECTS Pabio (NO) 1997-09-17 EP claimed
CN-1148811-A Compound having antihypertensive, cardioprotective, anti-ischemic and antilipolytic functions RHONE POULENC RORER PHARMA (US) 1997-04-30 CN claimed
WO-1996017954-A1 CHEMICAL LABELLING OF OBJECTS PABIO (DK) 1996-06-13 WO claimed