Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 4/20 | 0.38 |
| ▸ | MMP3 | P08254 | 4/20 | 0.38 |
| ▸ | MMP9 | P14780 | 4/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21320398 | 0.86 | CHRNA1 (0.49) | F2 | |
| SCHEMBL17177645 | 0.76 | F10 (0.43) | F2PRSS1TACR1TACR3 | |
| SCHEMBL23052583 | 0.74 | MMP1 (0.47) | PRSS1PRSS2PRSS3TLR2CPB2 | |
| SCHEMBL21081686 | 0.74 | MMP1 (0.47) | PRSS1PRSS2PRSS3TLR2CPB2 | |
| SCHEMBL1362526 | 0.73 | CTSS (0.41) | F2PRSS1 | |
| SCHEMBL6156498 | 0.73 | CTSS (0.41) | F2PRSS1TACR1TACR3 | |
| SCHEMBL29313314 | 0.72 | QRFPR (0.49) | — | |
| SCHEMBL29313281 | 0.72 | QRFPR (0.49) | — | |
| SCHEMBL22297882 | 0.72 | SIRT6 (0.46) | TLR2MMP1MMP3MMP9 | |
| SCHEMBL22297879 | 0.72 | SIRT6 (0.43) | F2TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3130608-A1 | (ANTI-HER2 ANTIBODY)-DRUG CONJUGATE | Daiichi Sankyo Co., Ltd. (JP) | 2017-02-15 | — | — | EP | disclosed |