Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 3/20 | 0.49 |
| ▸ | CHRNG | P07510 | 3/20 | 0.49 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.49 |
| ▸ | CHRND | Q07001 | 3/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | QRFPR | Q96P65 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313314 | 0.86 | QRFPR (0.49) | QRFPRCALCRLOPRK1 | |
| SCHEMBL29313281 | 0.86 | QRFPR (0.49) | QRFPRCALCRLOPRK1 | |
| SCHEMBL18515736 | 0.86 | F2 (0.41) | F2 | |
| SCHEMBL18556709 | 0.85 | OPRD1 (0.51) | QRFPRCALCRLOPRD1OPRM1OPRK1 | |
| SCHEMBL18515809 | 0.82 | OPRD1 (0.51) | CHRNA1CHRNGCHRNB1CHRNDCHRNB2 | |
| SCHEMBL29569077 | 0.82 | GNPAT (0.62) | CHRNA1CHRNGCHRNB1CHRNDCHRNB2 | |
| SCHEMBL17029474 | 0.82 | CHRNB2 (0.54) | CHRNA1CHRNGCHRNB1CHRNDCHRNB2 | |
| SCHEMBL29540107 | 0.82 | ERAP2 (0.55) | CHRNA1CHRNGCHRNB1CHRNDOPRD1 | |
| SCHEMBL18515624 | 0.81 | OPRD1 (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4OPRD1 | |
| SCHEMBL15840456 | 0.81 | CTSL (0.54) | CHRNB2CHRNB4CHRNA3CHRNA4OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3130608-B1 | (ANTI-HER2 ANTIBODY)-DRUG CONJUGATE | DAIICHI SANKYO CO LTD (JP) | 2019-09-04 | — | — | EP | disclosed |