Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18516381 | 0.88 | TSHR (0.65) | METKDRTSHRRAB9AKMT2A | |
| SCHEMBL8327094 | 0.84 | TSHR (0.59) | FFAR1TSHRSMN1; SMN2KMT2AMAP2K1 | |
| SCHEMBL24499181 | 0.82 | SMN1; SMN2 (0.53) | FFAR1TSHRSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL29965698 | 0.82 | SMN1; SMN2 (0.53) | FFAR1TSHRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7930522 | 0.82 | MAP2K1 (0.56) | FFAR1TSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL20679600 | 0.82 | SMN1; SMN2 (0.53) | FFAR1TSHRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2176371 | 0.81 | RAB9A (0.68) | NAMPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL5621845 | 0.80 | CYP1A2 (0.51) | FFAR1TSHRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL24750653 | 0.79 | MAP2K1 (0.53) | FFAR1TSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2192767 | 0.79 | ALDH1A1 (0.60) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957498-B1 | INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING | METHYLGENE INC (CA) | 2017-02-15 | — | — | EP | disclosed |