SCHEMBL185163

SCHEMBL185163

CCCCCCCCCCCCCCONOCCCCCCCCCCCCCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.47
TSHR P16473 1/20 0.47
EPHX1 P07099 1/20 0.43
MEN1 O00255 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPT P10636 1/20 0.42
CA1 P00915 8/20 0.41
CA2 P00918 8/20 0.41
CA9 Q16790 7/20 0.41
LPAR3 Q9UBY5 6/20 0.41
LPAR2 Q9HBW0 5/20 0.41
CA12 O43570 3/20 0.41
CA7 P43166 3/20 0.41
CA14 Q9ULX7 3/20 0.41
LPAR1 Q92633 2/20 0.41
CA3 P07451 2/20 0.41
CA4 P22748 2/20 0.41
CA6 P23280 2/20 0.41
CA5A P35218 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16053329 1.00 THRB (0.47) THRBTSHREPHX1MEN1HTT
SCHEMBL8006623 1.00 THRB (0.47) THRBTSHREPHX1MEN1HTT
SCHEMBL6264096 1.00 THRB (0.47) THRBTSHREPHX1MEN1HTT
SCHEMBL295951 1.00 THRB (0.47) THRBTSHREPHX1MEN1HTT
SCHEMBL4638313 1.00 THRB (0.47) THRBTSHREPHX1MEN1HTT
SCHEMBL8044051 0.97 THRB (0.41) THRBTSHREPHX1MEN1HTT
SCHEMBL2340182 0.88 ADRB2 (0.45) THRBTSHRCA1CA2
SCHEMBL29766147 0.85 EPHX1 (0.42) THRBTSHREPHX1MEN1HTT
SCHEMBL10833063 0.84 GBA1 (0.44) THRBEPHX1MEN1HTTKMT2A
SCHEMBL15282804 0.80 EPHX1 (0.46) THRBTSHREPHX1MEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1718271-B1 STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS BASF SE (DE) 2014-10-08 EP claimed
EP-3684858-A1 ADDITIVE MIXTURE BASF SE (DE) 2020-07-29 EP disclosed
WO-2019053187-A1 ADDITIVE MIXTURE BASF SE (DE) 2019-03-21 WO disclosed
WO-2019008002-A1 PHENOLIC METAL SALTS AND THEIR PHENOLIC ACIDS AS POLYMER STABILIZERS BASF SE (DE) 2019-01-10 WO disclosed
EP-3019474-A1 NOVEL LIGHT STABILIZERS BASF SE (DE) 2016-05-18 EP disclosed
WO-2015004580-A1 NOVEL LIGHT STABILIZERS BASF SE (DE) 2015-01-15 WO disclosed
EP-2640777-B1 STABILIZER COMPOSITION FOR POLYMERS BASF SE (DE) 2015-01-07 EP disclosed
EP-2640777-A1 STABILIZER COMPOSITION FOR POLYMERS BASF SE (DE) 2013-09-25 EP disclosed
WO-2012065919-A1 STABILIZER COMPOSITION FOR POLYMERS BASF SE (DE) 2012-05-24 WO disclosed
EP-2402390-A1 Particles with a hindered amine light stabilizer and a microporous organic polymer BASF SE (DE) 2012-01-04 EP disclosed
EP-1988773-A1 ANTIMICROBIAL COMPOUNDS Ciba Specialty Chemicals Holding Inc. (CH) 2008-11-12 EP disclosed
WO-2007099042-A1 ANTIMICROBIAL COMPOUNDS CIBA HOLDING INC. (CH) 2007-09-07 WO disclosed
EP-1749051-A1 FLAME-RETARDANTS Ciba Specialty Chemicals Holding Inc. (CH) 2007-02-07 EP disclosed
WO-2005118697-A9 FLAME-RETARDANTS CIBA SC HOLDING AG (CH) 2006-03-09 WO disclosed
WO-2005118697-A1 FLAME-RETARDANTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-12-15 WO disclosed
EP-0046271-B1 PHOTOSENSITIVE COMPOSITIONS AND ELEMENTS CONTAINING SUBSTITUTED HYDROXYLAMINE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-10-19 EP disclosed