SCHEMBL4638313

SCHEMBL4638313

CCCCCCCCCCCCCCCCCCONOCCCCCCCCCCCCCCCCCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.47
TSHR P16473 1/20 0.47
EPHX1 P07099 1/20 0.43
MEN1 O00255 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPT P10636 1/20 0.42
CA1 P00915 8/20 0.41
CA2 P00918 8/20 0.41
CA9 Q16790 7/20 0.41
LPAR3 Q9UBY5 6/20 0.41
LPAR2 Q9HBW0 5/20 0.41
CA12 O43570 3/20 0.41
CA7 P43166 3/20 0.41
CA14 Q9ULX7 3/20 0.41
LPAR1 Q92633 2/20 0.41
CA3 P07451 2/20 0.41
CA4 P22748 2/20 0.41
CA6 P23280 2/20 0.41
CA5A P35218 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16053329 1.00 THRB (0.47) THRBTSHREPHX1MEN1HTT
SCHEMBL185163 1.00 THRB (0.47) THRBTSHREPHX1MEN1HTT
SCHEMBL8006623 1.00 THRB (0.47) THRBTSHREPHX1MEN1HTT
SCHEMBL6264096 1.00 THRB (0.47) THRBTSHREPHX1MEN1HTT
SCHEMBL295951 1.00 THRB (0.47) THRBTSHREPHX1MEN1HTT
SCHEMBL8044051 0.97 THRB (0.41) THRBTSHREPHX1MEN1HTT
SCHEMBL2340182 0.88 ADRB2 (0.45) THRBTSHRCA1CA2
SCHEMBL29766147 0.85 EPHX1 (0.42) THRBTSHREPHX1MEN1HTT
SCHEMBL10833063 0.84 GBA1 (0.44) THRBEPHX1MEN1HTTKMT2A
SCHEMBL15282804 0.80 EPHX1 (0.46) THRBTSHREPHX1MEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240075722-A1 IRRADIATION STERILISABLE PACKAGING MATERIAL AND STABILIZED POLYOLEFIN FILM FOR USE THEREIN TETRA LAVAL HOLDINGS & FINANCE S.A. (CH) 2024-03-07 US disclosed
EP-3428228-A1 3-PHENYL-BENZOFURAN-2-ONE DERIVATIVES CONTAINING PHOSPHORUS AS STABILIZERS BASF SE (DE) 2019-01-16 EP disclosed
EP-3405519-A1 ADDITIVE MIXTURE FOR STABILIZATION OF POLYOL AND POLYURETHANE BASF SE (DE) 2018-11-28 EP disclosed
EP-3177681-B1 3-PHENYL-BENZOFURAN-2-ONE DIPHOSPHITE DERIVATIVES AS STABILIZERS BASF SE (DE) 2018-09-12 EP disclosed
US-10072136-B2 3-phenyl-benzofuran-2-one diphosphite derivatives as stabilizers BASF SE (DE) 2018-09-11 US disclosed
EP-3107959-B1 3-PHENYL-BENZOFURAN-2-ONE DERIVATIVES CONTAINING PHOSPHORUS AS STABILIZERS BASF SE (DE) 2018-07-25 EP disclosed
EP-3334780-A1 3-PHENYL-BENZOFURAN-2-ONE DERIVATIVES CONTAINING PHOSPHORUS AS STABILIZERS BASF SE (DE) 2018-06-20 EP disclosed
EP-2872496-B1 POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL]DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL BASF SE (DE) 2018-02-28 EP disclosed
US-20170226323-A1 3-PHENYL-BENZOFURAN-2-ONE DIPHOSPHITE DERIVATIVES AS STABILIZERS BASF SE (DE) 2017-08-10 US disclosed
WO-2017125291-A1 ADDITIVE MIXTURE FOR STABILIZATION OF POLYOL AND POLYURETHANE BASF SE (DE) 2017-07-27 WO disclosed
EP-1937698-A1 STABILIZATION OF POLYOLEFINS WITH LIQUID CYCLIC PHOSPHITES Ciba Holding Inc. (CH) 2008-07-02 EP disclosed
EP-1910455-A1 STABILIZATION OF POLYOLEFINS WITH LIQUID TRIS-(MONO-ALKYL)PHENYL PHOSPHITES Ciba Specialty Chemicals Holding Inc. (CH) 2008-04-16 EP disclosed
WO-2007042431-A1 STABILIZATION OF POLYOLEFINS WITH LIQUID CYCLIC PHOSPHITES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-04-19 WO disclosed
WO-2007009916-A1 STABILIZATION OF POLYOLEFINS WITH LIQUID TRIS-(MONO-ALKYL)PHENYL PHOSPHITES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-01-25 WO disclosed
EP-1003811-B1 OLEFIN POLYMER COMPOSITION HAVING LOW SMOKE GENERATION AND FIBER, FILM AND FABRIC PREPARED THEREFROM BASELL POLIOLEFINE SPA (IT) 2004-01-02 EP disclosed
EP-0924251-B1 Ductile, gamma radiation resistant polyolefin composition and articles produced therefrom BASELL NORTH AMERICA INC (US) 2003-08-13 EP disclosed
US-6172153-B1 STABILIZERS FOR MAKING FILM, FIBER AND FABRIC HAVING LOW SMOKE GENERATION FROM A POLYOLEFIN POLYMER CONTAINS A STABILIZING SYSTEM COMPRISING A PHOSPHITE AND A N,N-DIALKHYDROXYLAMINE; AN ACID NEUTRALIZER, A PROCESSING AID MONTELL NORTH AMERICA INC. 2001-01-09 US disclosed
US-5994436-A BLEND CONTAINING N,N-DIALKYLHYDROXYLAMINE AND A POLYSILOXANE MONTELL NORTH AMERICA INC. (US) 1999-11-30 US disclosed
EP-0924251-A1 Ductile, gamma radiation resistant polyolefin composition and articles produced therefrom MONTELL NORTH AMERICA INC. (US) 1999-06-23 EP disclosed
EP-0311568-A2 Long chain N-alykl-alpha-alkyl nitrones and their use as stabilizers CIBA-GEIGY AG (CH) 1989-04-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170226323-A1 3-PHENYL-BENZOFURAN-2-ONE DIPHOSPHITE DERIVATIVES AS STABILIZERS PIR, FIP1L1, IKZF1 THRB 4672/4885TSHR 4829/4885EPHX1 1914/4885
US-10072136-B2 3-phenyl-benzofuran-2-one diphosphite derivatives as stabilizers PIR, FIP1L1, IKZF1 THRB 4672/4885TSHR 4829/4885EPHX1 1914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.