Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14080195 | 0.79 | DPP4 (0.40) | ACEPOLB | |
| SCHEMBL6389769 | 0.79 | ACE (0.41) | ACEPOLBL3MBTL1 | |
| SCHEMBL11432958 | 0.79 | ACE (0.41) | ACEPOLBL3MBTL1 | |
| SCHEMBL9743696 | 0.77 | NPC1 (0.55) | — | |
| SCHEMBL18519489 | 0.76 | DPP4 (0.36) | SPHK1POLBL3MBTL1 | |
| SCHEMBL14453256 | 0.75 | ACE (0.40) | ACE | |
| SCHEMBL19658296 | 0.75 | ACE (0.44) | SPHK1ACE | |
| SCHEMBL10421372 | 0.75 | DPP4 (0.56) | ACEPOLBL3MBTL1 | |
| SCHEMBL4589694 | 0.75 | POLB (0.37) | ACEPOLBL3MBTL1 | |
| SCHEMBL21430566 | 0.75 | DPP4 (0.56) | ACEPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205309-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-11-30 | — | — | WO | disclosed |