Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUT5 | Q11128 | 1/20 | 0.55 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HINT1 | P49773 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | KRAS | P01116 | 2/20 | 0.45 |
| ▸ | PNP | P00491 | 2/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.44 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31583575 | 0.92 | FUT5 (0.53) | FUT5NT5EHPGDHPRT1TGM2 | |
| SCHEMBL30612754 | 0.89 | HPGD (0.54) | FUT5NT5EHPGDHPRT1HINT1 | |
| SCHEMBL20833471 | 0.87 | HPGD (0.51) | FUT5NT5EHPGDHPRT1TGM2 | |
| SCHEMBL21539237 | 0.86 | FUT5 (0.48) | FUT5NT5EHPGDHPRT1TGM2 | |
| SCHEMBL21539254 | 0.86 | FUT5 (0.50) | FUT5NT5EHPGDHPRT1TGM2 | |
| SCHEMBL25711923 | 0.84 | HINT1 (0.50) | FUT5NT5EHPGDHPRT1HINT1 | |
| SCHEMBL12714596 | 0.84 | FUT5 (0.66) | FUT5NT5EHPRT1TGM2POLB | |
| Phosphoric Acid SCHEMBL16213328 | 0.83 | NT5E (0.54) | FUT5NT5EHPGDHPRT1TGM2 | |
| SCHEMBL22326749 | 0.83 | FUT5 (0.53) | FUT5NT5ETGM2 | |
| SCHEMBL12714572 | 0.82 | FUT5 (0.61) | FUT5NT5EHPRT1TGM2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044206-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044206-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | STING1, CGAS, IFNAR1 | FUT5 4404/4885NT5E 1372/4885HPGD 1291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.